The main objective of this study was determining the prevalence and antibiotics resistance pattern of Salmonella and Shigella\nsp. from diarrheal patients attending Nekemte Referral Hospital. A total of 422 patients were included in the study and their\nsociodemographic and clinical information was collected using questionnaire. Stool samples of the patients were collected and\nprocessed following standard bacteriological protocols. Presumptive colonies of Salmonella and Shigella species were identified and\nsubcultured to their respective genera by standard biochemical tests. Antibiotics susceptibility of the isolates was tested using disk\ndiffusion assay.The prevalences of Salmonella and Shigella sp. among the patientswere 7.1% and 2.1%, respectively.The antimicrobial\nsusceptibility test results of the isolates showed that they are highly resistant to amoxicillin (30
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