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Inventi Impact: Molecular Modeling

Articles

  • Inventi:pmm/19466/16
    3D QSAR and Pharmacophore Identification on 2-Arylbenzoxazoles Derivatives as Cholesteryl Ester Transfer Protein Inhibitors
    15-Jul-2016 Research 2016 : July - September
    P B Choudhari*, S A Desai, S S Kumbhar, S V Khare, P P Subramani

    Cholesteryl ester transfer protein (CETP) is responsible for the transfer of cholesteryl esters from antiatherogenic HDLs to proatherogenic apolipoprotein B. A deficiency of CETP is associated with increased HDL levels and decreased LDL levels, a profile that is typically antiatherogenic. Inhibition of CETP may act as potential target for antihyperlipidemic drug design. The current manuscript deals with the 3D QSAR, pharmacophore identification of some reported CETP inhibitors.

    How to Cite this Article
    P B Choudhari, S A Desai, S S Kumbhar et al. 3D QSAR and Pharmacophore Identification on 2-Arylbenzoxazoles Derivatives as Cholesteryl Ester Transfer Protein Inhibitors. Inventi Impact: Molecular Modeling, 2016(3):146-150, 2016.
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