The main objective of this work was to study the physicochemical characterization of naturally available Fagopyrum esculentum (buckwheat) seed gum as a novel biodegradable pharmaceutical excipient. As buckwheat seed gum was being explored for the first time for its pharmaceutical application, physicochemical, rheological and stability studies with preservatives were conducted. The rheological results showed that buckwheat gum dispersion possesses dilatancy. It was observed that the buckwheat seed gum followed a non-Newtonian flow, which was confirmed by the existence of a nonlinear relationship between apparent viscosity and shear rate. The DSC profile showed endothermic comparatively sharp peak found at 279.81°C which was close to melting point of buckwheat gum. Thus the study confirmed the successful characterization of buckwheat seed gum. It showed that it can be used as an excipient for pharmaceutical products because of its abundant availability, reliability, efficiency, ecofriendly and economical features. And it would be a good substitute for synthetic polymers.
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