In this study, turpentine oil was used for enhancing the transdermal penetration of diclofenac\r\ndiethylamine (DDEA) from matrix patches prepared using carboxypolymethylene (CPM) and ethyl\r\ncellulose (EC) by solvent evaporation technique. The drug matrix film was subjected to different\r\nphysical testes like moisture content, moisture uptake and flatness, in vitro release and permeation\r\nstudies and ex vivo permeation studies. In vitro permeation studies were performed across artificial\r\nskin, while ex vivo across rabbit abdominal skin. The effect of increasing concentration of turpentine oil\r\non transdermal permeation of diclofenac diethylamine was studied on Franz cell apparatus. The results\r\nobtained were encouraging showing an increase in transdermal permeation with an increase in\r\nturpentine oil.
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