Core-shell beads loaded with betamethasone were developed using co-axial prilling as\nproduction technique and pectin plus alginate as polymeric carriers. During this study, many\noperative conditions were intensively investigated to find the best ones necessary to produce\nuniform core-shell particle systems in a reproducible way. Particularly, feed solutionsâ?? composition,\npolymers mass ratios and the effect of the main process parameters on particles production,\nmicromeritics, inner structure, drug loading and drug-release/swelling profiles in simulated\nbiological fluids were studied.......................................
Loading....