Insomnia is a common problem which includes wide variety of sleep disturbances, like difficulty in falling asleep, early or frequent awaking etc. Sedative-hypnotics are the drugs which reduce anxiety and produce sleep. Use of sedative-hypnotics is one approach to therapy of insomnia. Sedative-hypnotics can induce wide range of central effects from mild sedation to hypnosis. The drugs used as sedative-hypnotics have certain limitations in their use because of their side effect such as idiosyncrasy, hypersensitivity, tolerance and dependence. The interest lies in area of modification of a drug so as to reduce its side effects. Another interesting area is the discovery of herbal remedies producing sedation and hypnosis.
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