White horehound (Marrubium vulgare L.), is a grey-leaved perennial herb, belonging to\nLamiaceae family, distributed in Eurasia and northern Africa. Despite the fact that M. vulgare has\nbeen used since ancient times in treating diverse diseases, it is only in the last decade or so that\nscientists have been able to lay the foundation for its potential pharmacological actions from the\nresults observed through the prism of ethnopharmacological use of this species. The novelty of this\nstudy was that subcritical water extraction, acknowledged as a powerful extraction technology to\nrecover phenolic compounds, was coupled with spray drying. The subcritical horehound extract,\nobtained using optimal process parameters, was used as a liquid feed in spray drying. Maltodextrin\nwas used as a carrier in a concentration of 10%. Thus, two M. vulgare powders, carrier-free and 10%\nMD, were produced. Comprehensive powders characterization was conducted in order to evaluate\ntheir quality. Results confirmed that spray drying can be used as a method of choice for obtaining\nhigh quality horehound powders which kept the amorphous structure constant after 6 months.
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