Nephrotic Syndrome (NS) is one of the most frequent glomerular diseases seen in children. The common causes for NS include immunological dysfunction, genetical abnormalities or may be idiopathic. The signs and symptoms include edema, albuminuria, hypoalbuminemia, hyperlipidemia, high blood pressure, hematuria, decreased urine out-put volume. A 12 year old girl presented with complaints of painless brown hematuria, azotemia, decreased urine out-put volume and swelling of legs since 10 days. The case was diagnosed as proliferative glomerulonephritis with predominant mesangial proliferation and mild exudative change. The patient was treated with Tab.Deflazacort 30 mg, Tab.Amlodipine 2.5 mg, Tab.Pantoprazole and Calcium gluconate syrup 5 ml. In this case, the etiology was unknown and found to be idiopathic. The patient’s symptoms are found to be reduced and the condition of the patient is good.
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