The interaction of the immune system with cancer is complex, but new approaches are\nresulting in exciting therapeutic benefits. In order to enhance the immune response to cancer, immune\ntherapies seek to either induce high avidity immune responses to tumour specific antigens or to\nconvert the tumour to a more pro-inflammatory microenvironment. Strategies, including vaccination,\noncolytic viruses, and adoptive cell transfer all seek to induce anti-tumour immunity. To overcome\nthe suppressive tumour microenvironment checkpoint inhibitors and modulators of regulatory\ncell populations have been investigated. This review summarizes the recent advances in immune\ntherapies and discusses the importance of combination therapies in the treatment of cancers.
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