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Inventi Impact: Chemical Engineering

Articles

  • Inventi:eche/81811/25
    Chiral Method Development Using Polysaccharide-Based Chiral Stationary Phase (CSP) and Investigation of Chiral Column Degradation and Regeneration
    28-Mar-2025 Research 2025 : April-June
    Hua Zhao, Mary Ababat, Kyle Leeman, John Tucker

    Two polysaccharide-based chiral stationary phase columns were evaluated to improve the previous partial chiral peak separation to a baseline-resolved separation of the INGREZZA® drug substance and its diastereomers. Moreover, the tailing factor (Tf) variation was studied to investigate chiral column degradation and regeneration and to optimize chiral column performance and efficiency.

    How to Cite this Article
    Attribution/ CC Compliant Citation: Zhao, Hua, et al. "Chiral Method Development Using Polysaccharide-Based Chiral Stationary Phase (CSP) and Investigation of Chiral Column Degradation and Regeneration." American Journal of Analytical Chemistry 15.12 (2024): 395-406. https://doi.org/10.4236/ajac.2024.1512026 https://creativecommons.org/licenses/by/4.0/ Some formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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