Currently, one of the greatest health challenges worldwide is the resistance to antibiotic\ndrugs, which has led to the pursuit of new alternatives for the recovery of biological activity, where the\nuse of different types of nano-systems has shown an interesting potential. In this study, we evaluated\nthe antibiotic activity of a model drug (ampicillin) encapsulated within coated-nanoliposomes on\nstrains of Staphylococcus aureus with different antibiotic-resistance degrees. Hence, liposomes were\nelaborated by the ethanol injection method and were coated with a cationic polymer (Eudragit\nE-100) through the layer-by-layer process. Liposome characterization, such as size, polydispersity,\nzeta potential, and encapsulation efficiency were determined using dynamic light scattering and\nultrafiltration/centrifugation techniques. Although biological activity was evaluated using three\nATCC strains of S. aureus corresponding to ATCC 25923 (sensitive), ATCC 29213 (resistant) and ATCC\n43300 (very resistant). The results showed changes in size ...............
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