This study presents the formulation of two natural antioxidant creams based on an oil-inwater emulsion system, incorporating either hydroxycitrate (HCA) from Garcinia cambogia (Gaertn.) or red wine powder (RWP) derived from Aglianico del Vulture red wine (Vitis vinifera L.). HCA, a derivative of citric acid, and RWP, rich in polyphenolic compounds, were chosen for their bioactive properties. The creams underwent a series of in vitro tests to assess their stability, cytocompatibility, and antioxidant properties. Cellular assays using HaCaT keratinocytes showed that both formulations were effective in reducing blue light-induced oxidative damage.
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