The study aimed to evaluate the in vitro properties of a new gel formulation (P-3086) as anti-aging\ntreatment. Two in vitro methods aimed to assess and compare the efficacy of the gel formulation in\nreducing oxidative damages, artificially induced by UVA on skin-derived keratinocytes and in\npromoting the synthesis of collagen, compared with other four formulations. P-3086 reduced\nreactive oxygen species production after UVA stress with the highest effect observed at 0.016\nmg/ml and 0.031 mg/ml concentration. P-3086 also promoted the collagen synthesis faster when\ncompared with other formulations. The new gel product, based on hyaluronic acid, Vitamin E and\nHumulus lupulus, showed a good efficacy as anti-aging effect reducing the oxidative damages derived\nby the action of ROS, moreover stimulating the synthesis of one of the components of the\nconnective tissue, the collagen.
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