Dermatologic physiology and aesthetics are profoundly connected.\nInflammatory stimuli abound in the environment, and have the potential to impact both the\nphysiology and aesthetics of the integument. Inflammation results in a compromised\nepidermal barrier, impaired moisture retention, erythema, scale and pigment alteration. The\nadvent of nanotechnology has introduced a variety of new approaches to preserving skin\ncosmesis in the face of inflammation. In this article, we review the architecture and\nphysiology of the epidermal barrier, describe the pathological and aesthetic effects of\ninflammation, and report recent advances in the development of nanomaterials to offset the\naesthetic impact of inflammation.
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