In previous studies, Perilla frutescens pomace was shown to contain bioactive phenolic\ncompounds and good anti-oxidative activity. However, reports about collagenase activity and\nmelanogenesis inhibitory effects of P. frutescens pomace are limited. This study aimed to evaluate the\nbioactivity of P. frutescens pomace extract and incorporate the extract into a cosmetic formulation for\nevaluating its effects on collagenase and melanogenesis inhibition on human skin. The P. frutescens\nseeds after an oil pressing process were extracted with ethanol (70% v/v) in order to examine\nthe remaining phytochemical compounds, the bioactivity in pomace perilla, and its efficacy as\na skincare product. In this study, total phenolic and total flavonoid contents of P. frutescens\nseed extract (PFSE) were determined using spectrophotometry. The free radical scavenging\nactivity was determined with......................
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