Chitosonic�® Acid, carboxymethyl hexanoyl chitosan, is a novel chitosan material that\r\nhas recently been accepted by the Personal Care Products Council as a new cosmetic ingredient\r\nwith the INCI (International Nomenclature of Cosmetic Ingredients) name Carboxymethyl\r\nCaprooyl Chitosan. In this study, we analyze several important cosmetic characteristics of\r\nChitosonic�® Acid. Our results demonstrate that Chitosonic�® Acid is a water-soluble chitosan\r\nderivative with a high HLB value. Chitosonic�® Acid can form a nano-network structure when\r\nits concentration is higher than 0.5% and can self-assemble into a nanosphere structure when\r\nits concentration is lower than 0.2%. Chitosonic�® Acid has potent antimicrobial activities\r\nagainst gram-positive bacteria, gram-negative bacteria and fungus. Chitosonic�® Acid also has\r\nmoderate DPPH radical scavenging activity. Additionally, Chitosonic�® Acid exhibits good\r\nhydration activity for absorbing and retaining water molecules with its hydrophilic groups.\r\nFrom a safety point of view, Chitosonic�® Acid has no cytotoxicity to L-929 cells if its\r\nconcentration is less than 0.5%. Moreover, Chitosonic�® Acid has good compatibilities with\r\nvarious normal cosmetic ingredients. Therefore, we propose that Chitosonic�® Acid has the\r\npotential to be a widely used ingredient in various types of cosmetic products.
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