This study was aimed at investigating the antioxidant, whitening, and\r\nmoisture-retention properties of Lactobacillus rhamnosus spent culture supernatant (Lr-SCS)\r\nin cosmetic applications. Results reveal that Lr-SCS effectively and gradually scavenges\r\n1,1-diphenyl-2-picrylhydrazyl as well as 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic\r\nacid) radical cations, and increases reducing power in a dose-dependent manner.\r\nAdditionally, Lr-SCS can also suppress tyrosinase activity in vitro and effectively promote\r\nmoisture retention. Heat treatment at 100 �°C for 30 min does not influence the functions of\r\nLr-SCS. We conclude that Lr-SCS can be used effectively in skin care cosmetics.
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