Acoustic simulation has always played an important role in the development of new ultrasound imaging\r\ntechniques. In nonlinear ultrasound imaging particularly, the simulators are accurate but time-consuming, because\r\nof the high derivative order of the propagation equation and to the classic solution based on finite difference\r\nschemes. This article presents a fast 3D + t nonlinear ultrasound simulator, based on a generalized angular\r\nspectrum method, particularly fit for the graphics processing unit (GPU). Indeed, the Fourier domain approach\r\ndecreases the derivative order of the propagation, thus significantly speeding up the simulation time. The simulator\r\nwas implemented and optimized on a central processing unit (CPU) and a GPU, respectively. The processing times\r\nmeasured on two different graphic cards show that, compared to the CPU, GPU-based implementation is 3.5-13.6\r\ntimes faster.
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