A device for measuring biological small volume liquid samples in real time is appealing.\nOne way to achieve this is by using a microwave sensor based on reflection measurement. A prototype\nsensor was manufactured from low cost printed circuit board (PCB) combined with a microfluidic\nchannel made of polymethylsiloxane (PDMS). Such a sensor was simulated, manufactured, and\ntested including a vacuum powered sample delivery system with robust fluidic ports. The sensor\nhad a broad frequency band from 150 kHz to 6 GHz with three resonance frequencies applied in\nsensing. As a proof of concept, the sensor was able to detect a NaCl content of 125 to 155 mmol in\nwater, which is the typical concentration in healthy human blood plasma.
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