Frequency: Quarterly E- ISSN: Awaited P- ISSN: Abstracted/ Indexed in: Ulrich's International Periodical Directory, Google Scholar, SCIRUS
Quarterly published in print and online "Inventi Rapid: Medicine (Formerly Inventi Rapid: Holistic Medicines)" publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal focuses on alternative healthcare systems having wholesome or holy approach towards the health and disease management. Articles are invited from such areas as Ayurveda, Unani, Tibb, Homeopathy, Chiropractic, Osteopathy, Naturopathy, Massage Therapy, Meditation, Acupuncture, Crystals, Natural Diet and Herbal or Home Remedies.
Drugs can be fatal weaponry and we must memorize that the well-being of our patients are in our hands. Prescribing rationally must be related to every aspect of the art of general practice include patient-centered care, clinical skills and good judgment, familiarity of epidemiology. Ongoing medical education is imperative for the general practitioner. Little time is exhausted commerce with the essentials of therapeutics and all that is implicated in the suitable, rational usage of drugs....
The aim of the study was to assess knowledge, attitude and practices towards chronotherapy among final year students of medical, pharmacy and nursing. A prospective questionnaire based study was conducted in students of final year Medical, Pharmacy and Nursing of a tertiary care teaching hospital. The questionnaire consists of four parts which includes socio-demographics, knowledge, attitude and practice towards chronotherapeutics. Data collection was done in 300 students of final year medical, pharmacy and nursing. The filled questionnaires were evaluated using descriptive statistics and analysed using mean and standard deviation. With regards to mean total knowledge, results showed that there were significant difference between medical and pharmacy (p = .000) and also, medical and nursing (p = .000). Results also showed that there was significant difference between Pharmacy and Nursing (p = .000). In terms of mean total attitude, there was no significant difference between medical and pharmacy (p = 1), but there was a significant difference between Medical and Nursing (p = .000) and pharmacy and nursing (p = .000). In terms of mean total practice, there was a significant difference between medical and pharmacy (p = .000), as well as medical and nursing (p = .000) and also a significant difference between pharmacy and nursing (p = .000) in the results. From the study, it can be observed that, the final year students of medical faculty are more aware of chronotherapy in comparison to final year students of pharmacy and nursing faculties....
Polycystic ovary syndrome (PCOS) is one of the most common disorders that occur in women of any age due to an endocrine hormone imbalance. There is an urgent need for the development of novel natural PCOS medications free from adverse effects because the underlying cause of this condition has not yet been discovered. It was observed from a literature review on medicinal plant species that the phytochemicals present in the plants have the ability to increase the function of hormones for fertility. The goal of the ongoing research is to identify novel medication candidates from the medicinal plants that could be used to treat the target PCOS protein. An assessment of the medicinal plants revealed 145 phytochemicals that have been discovered through research. After in-silico screening for its drug likeness and structural reaction towards biological functions, only 23 compounds of the medicinal plants demonstrated the oral drug response, while other compounds failed to pass oral drug tests. Using docking studies, these compounds were further examined for their ability to bind to the PCOS protein Cytochrome P450 (CYP). The current findings suggest that the strongest binding affinity interactions with the target protein are only present in two compound. Based on the findings of this study, the predicted plant components can be identified and extracted for additional in-vitro and in-vivo testing to establish the safe dosage for PCOS patients....
Hospitalized patients who are initially on IV medication can be safely stepped down to an oral equivalent drug when the patient is clinically stable. The aim of the study was to retrospectively evaluate the practice of stepdown therapy in antibiotics and PPIs and its impact on length of hospital stay. The study was conducted in a tertiary care hospital with sample size of 200, each 100 patients for IV PPI and IV antibiotics. Case records of patients who received IV PPIs and antibiotics during the year 2020 were included in the study and Out patients were excluded. Out of all IV to Oral conversions, Sequential therapy was commonly used in PPIs and switch therapy was preferred for antibiotics. Average days of treatment with IV PPI in switch was 2 days and sequential was 2.217 days (p=0.733). Average days of treatment with oral PPI in switch was 3.333 days and sequential was 4.237 days (p=0.399). In case of antibiotics therapy average days of treatment with IV in stepdown was 6.677 days, switch 5.058 days and sequential is 4.059 days (p=0.00). In Oral therapy the average days of treatment with oral drugs were stepdown 5.323 days, switch 4.865 days and sequential therapy was 4.235 days (p=0.149). Length of hospital stay for patients had significantly decreased in PPIs switch therapy (p=0.337) and in case of antibiotics sequential therapy (p=0.001). Cephalosporins and penicillin were most commonly converted Antibiotics. Timely conversion of drugs from IV to oral therapy can reduce the length of hospitalization for patients....
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