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Quarterly published in print and online "Inventi Impact: Pharmacy Practice" publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. This journal focuses on discipline of pharmacy which involves developing the professional roles of pharmacists. The scope of the journal includes clinical pharmacy, hospital pharmacy, community pharmacy, pharmaceutical care, pharmacovigilance, social pharmacy, pharmacy education, process and outcome research, health promotion and education, health informatics, pharmacoeconomics and other related areas.
Eisenmenger syndrome is a chronic condition characterized by advanced pulmonary hypertension associated with congenital heart disease. Cyanotic system like bluish or grayish coloration of skin can be observed in the patients with Eisenmenger syndrome. Chest tightness, pain and shortness of breath, lesions, headaches, dizziness, easily tiring, fainting, numbness or tingling in fingers and/or toes are the most common symptoms. Severe pulmonary arterial hypertension is the basic diagnosis of Eisenmenger syndrome. The diagnosis of Eisenmenger syndrome can be made when the mean pressure in the pulmonary trunk which can be elevated beyond 25 mmHg while at rest and 30 mmHg while at exercising. This elevation is resulted from aggravating thrombotic processes, pulmonary artery remodeling and vasoconstriction. Use of antiarrhythmics, anticoagulants, diuretics and/or digitalis is included in the pharmacological treatment. The management aspects include behavioral modifications, awareness of potential medical risk factors and patient education. The drugs for pulmonary hypertension have not been modified the survival rate significantly yet. The prevention by early surgery is ideal, as little progress in management has been made. Progressive factors like high altitudes, anesthesia, estrogen contraception and pregnancy has to be avoided. Cooperation of the medical practitioners with specialists like cardiologists and awareness about complications should improve the patient’s outlook....
Nephrotic Syndrome (NS) is one of the most frequent glomerular diseases seen in children. The common causes for NS include immunological dysfunction, genetical abnormalities or may be idiopathic. The signs and symptoms include edema, albuminuria, hypoalbuminemia, hyperlipidemia, high blood pressure, hematuria, decreased urine out-put volume. A 12 year old girl presented with complaints of painless brown hematuria, azotemia, decreased urine out-put volume and swelling of legs since 10 days. The case was diagnosed as proliferative glomerulonephritis with predominant mesangial proliferation and mild exudative change. The patient was treated with Tab.Deflazacort 30 mg, Tab.Amlodipine 2.5 mg, Tab.Pantoprazole and Calcium gluconate syrup 5 ml. In this case, the etiology was unknown and found to be idiopathic. The patient’s symptoms are found to be reduced and the condition of the patient is good....
Vasmol ingestion with suicidal intension has increased among rural Indian population. There are increasing reports of vasmol poisoning cases because of easy availability and high lethality. Several brands are available in the market among that supervasmol 33 is a most popular hair dye. The main component of hair dye causing toxicity is paraphenylene-diamine (PPD). This compound causes oedema of the tongue, rhabdomyolysis and renal failure. Here we reported a 37 year old female consumed hair dye with liver enzymes and urine examinations were altered....
Main aim of Regulatory affairs in pharmaceutical industry is to protect human health. The purpose of drug is to diagnose, prevent or treat diseases or ailments in humans, they are products intimately linked with the advances in research and regulation. People and government spent money on drugs because of the role they can play in saving lives, restoring health, preventing diseases and stopping epidemics. But, in order to do so, drug must be safe, effective and of good quality. The primary components should be regulated by Drug Regulatory Agencies like, product registration, regulation of drug manufacturing, importation and distribution, regulation of drug promotion and information. The pharmaceutical industry, while pursuing an international market, is obliged to comply with national regulations. So, in this review article, an overview of few drug regulatory agencies: India, Europe, Japan, US is covered....
Factors associated with antibiotic use, resistance and safety have been well documented worldwide in the literature. Nevertheless, only few studies have been conducted in Tamil Nadu. The aim of this study was to assess the patient’s attitudes toward the use and knowledge of antibiotics, survey instrument included questions about the patient’s demographic information, familiarity with various antibiotics, attitudes toward the knowledge and safety use of antibiotics and the patient’s comfort level when discussing antibiotics. 79% believed that antibiotics are safe to treat common cold and cough. 15% of females showed inadequate knowledge about the safe use of antibiotics during pregnancy and nursing. 35% kept antibiotics at home for emergency use and 39% misused antibiotics as analgesics. 35% use left-over antibiotics without physicians’ consultation while 65% use antibiotics based on a relative advice. 90% of patients indicated that they were used the antibiotics without any counselling. Hence the remedy suggested for avoid the misuse of antibiotics in the overall population are emphasizing pharmacists role and responsibility in preventing antibiotic sale without prescription and consultation approaches and strategies that make patient expectations explicit without destructing physician patient relationship....
Now days there has been increasing trend for self-medication among the Indian population. Craving for medicine and self-medication has been part of mankind from one generation to another. People generally hold the view that medicines should be used in the event of any sickness or discomfort during the life time. The main objective of present study assessment of self medication practices among medical and non medical profession. The study was conducted on a sample of randomly selected pharmacy and degree students of Kakatiya University; Jawaharlal Nehru Technological University, Andhra Pradesh; the age of the students ranged from 17 years to 60 years both sex were questioning. A semi structured questionnaire was prepared; data was collected over 12 months period using self administered questionnaire. The study period was conducted from august 2012 to august 2013. Data collected, interview the medicos and non medicos who agreed to participate in the study during interview enquiring about the personal data. A total of 1002 out of 1050 questionnaires were completed filled returned to the researcher, giving a response data of 95.4%. Characteristically average age for the respondents was 26 years old and most responders were females (54.5%) of non medical professionals. The majorities reported to have health insurance living with in the area where a clinic or pharmacy is close and were mostly free from chronic disease. Approximately 73.05% of the respondents reported that they do practice self medication. Self medication was practiced by 17.6% of medical, 79.5% of non medical and others were found to be of 2.79% of 45.6% male and 54.5% female suggesting that the practice of self medication, in general was independent of gender or type of profession. The most common class of medication used in self medication was anti pyretic and analgesics particularly paracetamol which was reported by 59.6% of the respondents. Reasons for self medication noted are wide advertisements of medicines in televisions, news papers, magazines results in selection of inappropriate drugs for disease condition leading to the misjudgement of the disease resulted in drug complications and mortality rate....
Collaborative practice in health-care has proven to be an effective and efficient method
for the management of chronic diseases. This study describes a de novo collaborative practice
between a pharmacist and a family physician. The primary objective of the study is to describe
the collaboration model between a pharmacist and family physician. The secondary objective is
to describe the pharmacist workload. A list of patients who had at least one interaction with the
pharmacist was generated and printed from the electronic medical record. There were 389 patients
on the patient panel. The pharmacist had at least one encounter with 159 patients. There were
83 females. The most common medical condition seen by the pharmacist was hypertension. A total
of 583 patient consultations were made by the pharmacist and 219 of those were independent
visits. The pharmacist wrote 1361 prescriptions. The expanded scope of practice for pharmacists in
Alberta includes additional prescribing authority. The pharmacists’ education and clinical experience
gained trust from the family physician. These, coupled with the family physician’s previous positive
experience working with pharmacists made the collaboration achievable....
Approximately 40% of patients admitted to the medical intensive care unit (ICU) require mechanical ventilation. An accurate\nprediction of successful extubation in patients is a key clinical problem in ICUdue to the fact that the successful extubation is highly\nassociated with prolonged ICU stay.The prolonged ICU stay is also associated with increasing cost and mortality rate in healthcare\nsystem. This study is retrospective in the aspect of ICU. Hence, a total of 41 patients were selected from the largest academic\nmedical center in Taiwan. Our experimental results show that predicting successful rate of 87.8% is obtained from the proposed\npredicting function. Based on several types of statistics analysis, including logistic regression analysis, discriminant analysis, and\nbootstrap method, threemajor successful extubation predictors, namely, rapid shallowbreathing index, respiratory rate, and minute\nventilation, are revealed. The prediction of successful extubation function is proposed for patients, ICU, physicians, and hospital\nfor reference....
Introduction\nUnderstanding how pharmacy technicians and other pharmacy support workforce cadres assist pharmacists in the healthcare system will facilitate developing health systems with the ability to achieve universal health coverage as it is defined in different country contexts. The aim of this paper is to provide an overview of the present global variety in the technician and other pharmacy support workforce cadres considering; their scope, roles, supervision, education and legal framework.\n\nMaterial and methods\nA structured online survey instrument was administered globally using the Survey Monkey platform, designed to address the following topic areas: roles, responsibilities, supervision, education and legislation. The survey was circulated to International Pharmaceutical Federation (FIP) member organisations and a variety of global list serves where pharmaceutical services are discussed.\n\nResults\n193 entries from 67 countries and territories were included in the final analysis revealing a vast global variety with respect to the pharmacy support workforce.\n\nRoles and competency\nFrom no pharmacy technicians or other pharmacy support workforce cadres in Japan, through a variety of cadre interactions with pharmacists, to the autonomous practice of pharmacy support workforce cadres in Malawi.\n\nResponsibilities\nFrom strictly supervised practice with a focus on supply, through autonomous practice for a variety of responsibilities, to independent practice.\n\nSupervision\nFrom complete supervision for all tasks, through geographical varied supervision, to independent practice.\n\nEducation\nFrom on the job training, through certificate level vocational courses, to 3Ã¢â?¬â??4 year diploma programs.\n\nLegislation, regulation and liability\nFrom well-regulated and registered, through part regulation with weak implementation, to completely non-regulated contexts.\n\nConclusion\nThis paper documents wide differences in supervision requirements, education systems and supportive legislation for pharmacy support workforce cadres globally. A more detailed understanding of specific country practice settings is required if the use of pharmacy support workforce cadres is to be optimized....
Genetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic
information can be used to guide the selection and dosing of certain drugs. However,
the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a
formal structure, as well as concrete procedures and clearly defined responsibilities, may facilitate
and increase the use of PGx in clinical practice. Over 140 patient cases from an observational study in
Switzerland formed the basis for the design and refinement of a pharmacist-led pharmacogenetics
testing and counselling service (PGx service) in an interprofessional setting. Herein, we defined a
six-step approach, including: (1) patient referral; (2) pre-test-counselling; (3) PGx testing; (4) medication
review; (5) counselling; (6) follow-up. The six-step approach supports the importance of an
interprofessional collaboration and the role of pharmacists in PGx testing and counselling across
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