Current Issue : January - March Volume : 2018 Issue Number : 1 Articles : 5 Articles
Various unsaturated natural terpenes were selectively converted to the corresponding polychlorinated products in good yields\nusing iron acetylacetonate in combination with nucleophilic cocatalyst. The synthesized compounds were evaluated for their in\nvitro antifungal activity.The antifungal bioassays showed that 2c and 2d possessed significant antifungal activity against Fusarium\noxysporum f. sp. albedinis (Foa), Fusarium oxysporum f. sp. canariensis (Foc), and Verticillium dahliae (Vd)....
Various 2-(5-H/chloro-((piperazin-1-yl-methyl)-2-oxoindolin-3-ylidene)-N-substittuted hydrazine carbothioamides\n4aââ?¬â??j were synthesized. The compounds were screened and evaluated for their Ã?²-Lactamase inhibitory activity with potassium\nclavulanate as a standard, amongst screened and evaluated chemical compounds. The compound 4e shown highest Ã?²-Lactamase\ninhibitory activity which was equivalent to standard Ã?²-Lactamase inhibitor, potassium clavulanate....
A new series of tetrahydrocarbazole coupled 1,2-diazoles 4/5/6(aââ?¬â??o) in moderate to excellent yield was synthesized successfully via\nmulticomponent reaction approach by adoptingMichael type-addition of hydrazines on in situ generated ...
A series of 14 new (âË?â??)-gossypol Schiff bases and hydrazones have been synthesized via anin situ procedure in high yields. Structural\ndata showed that all target compounds exist as the enamine tautomer. Bioassays showed that several compounds exhibited cytotoxic\neffects against three human cancer cell lines. Compound 8a showed the greatest cytotoxic effect against hepatocellular carcinoma\n(HepG2), lung carcinoma (LU-1), and breast cancer (MCF-7) cell lines with IC50 values of 20.93, 13.58, and 9.40 ...
The crystal structure of ethyl 1-(2-(hydroxyimino)-2-phenylethyl)-3-phenyl-1H-pyrazole-5-carboxylate has been determined by Xray\nsingle crystal diffraction. The crystal of the title compound is the monoclinic space group P2/c with unit cell parameters of\n...
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