Current Issue : July - September Volume : 2018 Issue Number : 3 Articles : 5 Articles
Background. Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect in cancer patients. The aim of this\nreview was to assess the effectiveness of herbal medicine in preventing and treating CIPN. Methods. Randomised controlled trials\nwere included in this review. Extracting and assessing the data independently, two authors searched 13 databases. Results. Twentyeight\ntrials involving 2174 patients met the inclusion criteria. Although there were some exceptions, themethodological quality was\ntypically low. Seventeen trials reported the incidence rate of CIPN assessed by various tools and 14 showed a significant difference\nregarding the decrease of the incidence rate between the two groups. For clinical improvement, 12 trials reported it using various\ntools and 10 showed a significant difference between two groups. Two cases of adverse events occurred in one trial; the other nine\ntrials reported no adverse events. Conclusions.We found that herbal medicines in combination with and/or without other therapies\npotentially have preventive or therapeutic effects on CIPN. However, conclusions cannot be drawn because of the generally low\nquality of the methodology, the clinical heterogeneity, and the small sample size for each single herbal medicine. Trials that are\nmore rigorous and report sufficient methodological data are needed....
Despite the development ofmore researched and formulated orthodox medicines, herbal medicines continue to be well patronized\nfor persons across the world with some patrons concurrently using both forms, oblivious of the unwanted effects thatmay occur.\nUsing a multistage sampling procedure, a semistructured questionnaire was used to collect data in April 2016 from 240 informants\nfrom three selected hospitals and three herbal clinics in Tamale, a city in northern Ghana. Using Statistical Package for the Social\nSciences, binary logistic regression was used to determine sociodemographic predictors of concurrent use of herbal and orthodox\nmedicines. Orthodoxmedicines were the drug of choice for 54.2% and 49.2% of patrons of hospitals and herbal clinics, respectively.\nAlso, 67.5% of herbal clinic patrons used orthodox medicines, while 25.0% of hospital attendees used herbal medications prior to\ntheir visit to the health facilities. Up to 17.9% of respondents concurrently used herbal and orthodox medicines for their prevailing\nailment with age, less than 30 years being the only predictor of this habit (...
Introduction. Menstrual bleeding cessation is one of the most frequent gynecologic disorders among women in reproductive\nage. The treatment is based on hormone therapy. Due to the increasing request for alternative medicine remedies in the field\nof women�s diseases, in present study, it was tried to overview medicinal plants used to treat oligomenorrhea and amenorrhea\naccording to the pharmaceutical textbooks of traditional Persian medicine (TPM) and review the evidence in the conventional\nmedicine. Methods. This systematic review was designed and performed in 2017 in order to gather information regarding herbal\nmedications of oligomenorrhea and amenorrhea in TPM and conventional medicine. This study had several steps as searching\nIranian traditional medicine literature and extracting the emmenagogue plants, classifying the plants, searching the electronic\ndatabases, and finding evidences. To search traditional Persian medicine references, Noor digital library was used, which includes\nseveral ancient traditional medical references. The classification of plants was done based on the repetition and potency of the\nplants in the ancient literatures.Therequired data was gathered using databases such as PubMed, Scopus,Google Scholar, Cochrane\nLibrary, Science Direct, and web of knowledge. Results. In present study of all 198 emmenagogue medicinal plants found in TPM, 87\ncaseswere specified to bemore effective in treating oligomenorrhea and amenorrhea. In second part of present study,where a search\nof conventional medicine was performed, 12 studies were found, which had 8 plants investigated: Vitex agnus-castus, Trigonella\nfoenum-graecum, Foeniculum vulgare, Cinnamomum verum, Paeonia lactiflora, Sesamum indicum, Mentha longifolia, and Urtica\ndioica. Conclusion. Traditional Persian medicine has proposed many different medicinal plants for treatment of oligomenorrhea\nand amenorrhea. Although just few plants have been proven to be effective for treatment of menstrual irregularities, the results and\nthe classification in present study can be used as an outline for future studies and treatment....
Refractory nephrotic syndrome (RNS) is an immune-related kidney disease with poor clinical outcomes. Standard treatments\ninclude corticosteroids as the initial therapy and other immunosuppressants as second-line options. A substantial proportion\nof patients with RNS are resistant to or dependent on immunosuppressive drugs and often experience unremitting edema and\nproteinuria, cycles of remission and relapse, and/or serious adverse events due to long-term immunosuppression. Traditional\nChinese medicine has a long history of treating complicated kidney diseases and holds great potential for providing effective\ntreatments for RNS. This review describes the Chinese medical theories relating to the pathogenesis of RNS and discusses the\nstrategies and treatment options using Chinese herbal medicine. Available preclinical and clinical evidence strongly supports the\nintegration of traditional Chinese medicine and Western medicine for improving the outcome of RNS. Herbal medicine such as\nAstragalus membranaceus, Stephania tetrandra S. Moore, and Tripterygium wilfordii Hook F can serve as the alternative therapy\nwhen patients fail to respond to immunosuppression or as the complementary therapy to improve therapeutic efficacy and reduce\nside effects of immunosuppressive agents.Wuzhi capsules (Schisandra sphenanthera extract) with tacrolimus and tetrandrine with\ncorticosteroids are two herb-drug combinations that have shown great promise and warrant further studies...
Background and Aim. Spontaneous bacterial peritonitis (SBP) is one of the most common complications of liver cirrhosis.\nAntibiotics are the main treatment regimen of SBP. Traditional Chinese medicine Xuebijing injection has been used in such\npatients. Our study aimed to overview the efficacy of Xuebijing injection combined with antibiotics for the treatment of SBP.\nMethod. We searched the PubMed, Embase, China National Knowledge Infrastructure, VIP, and Wanfang databases. The search\nitems included ââ?¬Å?Xuebijingââ?¬Â, ââ?¬Å?peritonitisââ?¬Â, ââ?¬Å?liver cirrhosisââ?¬Â, and ââ?¬Å?randomââ?¬Â to identify all relevant randomized controlled trials\n(RCTs). The Cochrane risk of bias tool was used to assess the study quality. The odd ratios (ORs) with 95% confidence intervals\n(CIs) were calculated by using a random-effect model. Heterogeneity was also calculated. Results. A total of 9 RCTs were\nincluded. The study quality was unsatisfied. The overall (OR = 2.95, 95% CI = 1.97ââ?¬â??4.42, ...
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