Current Issue : April - June Volume : 2020 Issue Number : 2 Articles : 5 Articles
Cosmeceutical peptides have become an important topic in recent decades in both\nacademic and industrial fields. Many natural or synthetic peptides with different biological\nfunctions including anti-ageing, anti-oxidation, anti-infection and anti-pigmentation have been\ndeveloped and commercialized. Current cosmeceutical peptides have already satisfied most market\ndemand, remaining: â??cargos carrying skin penetrating peptide with high safetyâ? still an un-met\nneed. To this aim, a cell-penetrating peptide, CPPAIF, which efficiently transported cargos into\nepithelial cells was exanimated. CPPAIF was evaluated with cell model and 3D skin model following\nOECD guidelines without using animal models. As a highly stable peptide, CPPAIF neither irritated\nnor sensitized skin, also did not disrupt skin barrier. In addition, such high safety peptide had antiinflammation\nactivity without allergic effect. Moreover, cargo carrying activity of CPPAIF was\nassayed using HaCaT cell model and rapid CPPAIF penetration was observed within 30 min. Finally,\nCPPAIF possessed transepidermal activity in water in oil formulation without disruption of skin\nbarrier. All evidences indicated that CPPAIF was an ideal choice for skin penetrating and its antiinflammatory\nactivity could improve skin condition, which made CPPAIF suitable and attractive for\nnovel cosmeceutical product development....
Sacha inchi oil is a premier raw material with highly nutritional and functional features\nfor the foodstuff, pharmaceutical, beauty, and personal care industries. One of the most important\nfacts about this oil is the huge chemical content of unsaturated and polyunsaturated fatty acids.\nHowever, the current available information on the characterization of the triglyceride composition\nand the advance physicochemical parameters relevant to emulsion development is limited. Therefore,\nthis research focused on providing a detailed description of the lipid composition using high-resolution\ntandem mass spectrometry and thorough physicochemical characterization to find the value of the\nrequired hydrophilicâ??lipophilic balance (HLB). For this, a study in the interfacial tension was\nevaluated, followed by the assessment of different parameters such as creaming index, droplet size,\nviscosity, zeta potential, pH, and electrical conductivity for a series emulsified at thermal stress\ncondition. The results show that fatty acids are arranged into glycerolipids and the required HLB to\nachieve the maximum physical stability is around 8....
Inula helenium (IH) is known to possess antifungal, anti-bacterial, anti-helminthic, and antiproliferation\nactivities. Caesalpinia Sappan (CS) is known to reduce inflammation and improve blood\ncirculation. Based on their folkloric use, these plants are expected to be promising candidates for\npromoting hair growth and preventing hair loss. Moreover, these plants are rich sources of certain\nphytochemicals, which have been reported to promote hair growth. ........................
As the popularity of a cosmetic product on the market extensively depends on consumersâ??\nperception, it is important for the sensory evaluation to be accurate during the product developmental\nstage. The focus of this study was to develop a generic method for the quantitative assessment of\nthe sensory attributes of cosmetic creams. Four 100 g oil-in-water (O/W) model creams, containing\nloaded niosomes and their baselines (without niosomes), were formulated. Quantitative sensory\nevaluation of the formulated oil-in-water products were performed in three different stages: (a)\nappearanceâ??pourability (b) pick-up--firmness and elasticity/stretchability (c) rub-out--spreadability\nand stickiness, using rheological measurements. ............................
Ultraviolet (UV) radiation has been demonstrated to cause skin disorders, including sunburn\nand relative symptoms of prolonged exposure. It has been reported that sunscreens have beneficial\neffects in reducing the incidence of skin disorders (sunburn, skin aging, and immunosuppression)\nthrough their ability to absorb, reflect, and scatter UV. Many commercial products have recently been\nmanufactured from not only usual organic and inorganic UV filters, but also hybrid and botanical\ningredients using typical formulations (emulsion, gel, aerosol, and stick). Particularly, these products\nhave been supplemented with several preeminent properties to protect against the negative effects of\nnot only UVB, but also UVA. However, the use of sunscreen has faced many challenges, including\ninducing photoallergic dermatitis, environment pollution, and deficiency of vitamin D production.\nTherefore, consumers should efficiently apply suitable products to improve sun protection. as well as\nto avoid the side effects of sunscreen....
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