Current Issue : October - December Volume : 2020 Issue Number : 4 Articles : 5 Articles
We developed a Vital-signs-integrated Patient-assisted Intravenous opioid Analgesia (VPIA) analgesic\ninfusion pump, a closed-loop vital signs monitoring and drug delivery system which embodied in a novel\nalgorithm that took into account patientsâ?? vital signs (oxygen saturation, heart rate). The system aimed to allow\nresponsive titration of personalized pain relief to optimize pain relief and reduce the risk of respiratory depression.\nMoreover, the system would be important to enable continuous monitoring of patients during delivery of opioid\nanalgesia.\nMethods: Nineteen patients who underwent elective gynecological surgery with postoperative patient controlled\nanalgesia (PCA) with morphine were recruited. The subjects were followed up from their admission to the recovery\nroom/ ward for at least 24 h until assessment of patient satisfaction on the VPIA analgesic infusion pump.....................
Several neuraxial techniques have demonstrated effective post-cesarean section analgesia. According to\nprevious reports, it is likely that patient-controlled epidural analgesia (PCEA) without opioids is inferior to intrathecal\nmorphine (IM) alone for post-cesarean section analgesia. However, little is known whether adding PCEA to IM is effective\nor not. The aim of this study was to compare post-cesarean section analgesia between IM with PCEA and IM alone.\nMethods: Fifty patients undergoing elective cesarean section were enrolled in this prospective randomized study.\nPatients were randomized to one of two groups: IM group and IM + PCEA group. All patients received spinal....................
Spinal anesthesia is optimal choice for transurethral resection of the prostate (TURP), but the sensory\nblock should not cross the T10 level. With advancing age, the sensory blockade level increases after spinal injection\nin some patients with spinal canal stenosis. We optimize the dose of spinal anesthesia according to the decreased\nratio of the dural sac cross-sectional area (DSCSA), the purpose of this study is to hypothesis that if DSCSA is an\neffective parameter to modify the dosage of spinal anesthetics to achieve a T10 blockade in geriatric patients\nundergoing TURP.\nMethods: Sixty geriatric patients schedule for TURP surgery were enrolled in this study. All subjects were\nrandomized divided into two groups, the ultrasound (group U) and the control (group C) groups, patient\nreceive either a dose of 2 ml of 0.5% isobaric bupivacaine in group C, or a modified dose of 0.5% isobaric\nbupivacaine in group U. We measured the sagittal anteroposterior diameter (D) of the dural sac....................
Caudal ketamine has been shown to provide an effective and prolonged post-operative analgesia\nwith few adverse effects. However, the effect of caudal ketamine on the minimum local anesthetic concentration\n(MLAC) of ropivacaine for intra-operative analgesia is unclear.\nMethods: One hundred and sixty-nine children were randomized to five groups: Group C (caudal ropivacaine only),\nGroup K0.25 (caudal ropivacaine plus 0.25 mg/kg ketamine), Group K0.5 (caudal ropivacaine plus 0.5 mg/kg ketamine),\nGroup K0.75 (caudal ropivacaine plus 0.75 mg/kg ketamine), and Group K1.0 (caudal ropivacaine plus 1.0 mg/kg\nketamine). The primary outcome was the MLAC values of ropivacaine with/without ketamine for caudal block..............
Previous studies showed that remifentanil-induced anesthesia can inhibit surgical stress response in\nnon-diabetic adult patients and that low-dose glucose loading during anesthesia may attenuate fat catabolism.\nHowever, little is known about the influence of glucose loading on metabolism in elderly patients, whose condition\nmay be influenced by decreased basal metabolism and increased insulin resistance. We hypothesized that, in\nelderly patients, intraoperative low glucose infusion may attenuate the catabolism of fat without causing harmful\nhyperglycemia during remifentanil-induced anesthesia.\nMethods: Elderly, non-diabetic patients scheduled to undergo elective surgery were enrolled and randomized to\nreceive no glucose (0G group) or low-dose glucose infusion (0.1 g/kg/hr. for 1 h followed by 0.05 g/kg/hr. for 1 h;\nLG group) during surgery. Glucose, adrenocorticotropic hormone (ACTH), 3-methylhistidine (3-MH), insulin, cortisol,\nfree fatty acid (FFA), creatinine (Cr), and ketone body levels were measured pre-anesthesia, 1 h post-glucose\ninfusion, at the end of surgery, and on the following morning...............
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