Current Issue : January - March Volume : 2021 Issue Number : 1 Articles : 8 Articles
Background: Drainage of exudative retinal detachment may be necessary for either therapeutic or diagnostic\npurposes (or both). Here, we describe an external drainage technique for non-resolving vision-threatening\nexudative retinal detachment which combines the advantages of internal drainage (widefield viewing and\nintraocular pressure control using continuous anterior chamber infusion) with those of external drainage (drainage\nof sub-retinal fluid without vitrectomy).\nCase presentation: To illustrate this technique, we present a 13-year-old girl with macula-off exudative retinal\ndetachment secondary to Vogt-Koyanagi-Harada syndrome, which was unresponsive to aggressive medical\nmanagement.......................................
Background: To observe the changes in ocular biometric measurements after vitrectomy with silicone oil\ntamponade for rhegmatogenous retinal detachment (RRD) repair.\nMethods: Sixty-three phakic, macula-off RRD eyes underwent vitrectomy with silicone oil tamponade but not lens\nextraction were included in this retrospective study. Measurements of axial length (AL), anterior chamber depth\n(ACD), lens thickness (LT) using the new Zeiss IOLMaster 700 and derivative lens position (LP), relative lens position\n(RLP) and lens-retina distance (LRD) were compared and analyzed between preoperative and postoperative in\nphakic, macula-off eyes with RRD..............................
Background: Herpes simplex virus type 1 (HSV-1) keratitis is a major cause of corneal blindness in the world, and\nan in-depth understanding of its pathogenesis may help improve existing diagnosis and treatment. The purpose of\nthis study is to compare and analysis the total tear protein profile of HSV-1 epithelial keratitis patients, and to\nquantify the potential candidate biomarkers of HSV-1 epithelial keratitis.\nMethods: We investigated the proteome in tear fluid from three HSV-1 epithelial keratitis patients and three\nhealthy control subjects using nano-scale liquid chromatography-tandem mass spectrometry (nLC-MS/MS) analysis.\nFunctional annotation of differentially expressed proteins was done with the Gene Ontology (GO) analysis. ELISA\nwas done to quantify the potential candidate biomarkers in 26 clinical cases.\nResults: Tear fluid from three HSV-1 epithelial keratitis patients and three healthy control subjects contained a total\nof 1275 proteins and 326 proteins were unique to tear fluid of HSV-1 epithelial keratitis patients. Bioinformatics\nanalysis revealed that tear proteins from HSV-1 epithelial keratitis patients may be involved in metabolic processes,\nantigen presentation, inflammatory response, and in the TNF-mediated and T cell receptor pathways. Furthermore,\nIL1A, IL12B, DEFB4A, and CAMP, which are associated with the inflammatory response and inhibition of viral\ninfection, were significantly more abundant in the HSV-1 epithelial keratitis patients than in the healthy control\nsubjects.\nConclusions: This study reports the proteomic profile of tears in HSV-1 epithelial keratitis for the first time and\nidentifies a number of unique differentially expressed proteins....
Background: To evaluate the safety and effectiveness of the Visian Implantable Collamer Lens (ICL) implantation in\nhigh myopic patients with inactive Gravesâ?? ophthalmopathy (GO) by observing the changes of choroidal thickness\n(CT).\nMethods: Eight patients (16 eyes) with high myopia accompanied with inactive GO were selected as the\nexperimental group (group A) and 18 high myopic patients (36 eyes) without GO were selected as a control group\n(group B). The outcomes of uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BCVA), safety\nindex, efficacy index, intraocular pressure (IOP), vault, corneal endothelial count, and choroidal thickness (CT) were\nobserved. The values of CT were measured using swept-source optical coherence tomography (SS-OCT) scans.\nResults: The UCVA and BCVA in all operated eyes were better than that before surgery. The postoperative safety\nindex and efficacy index were 1.23 and 1.19 in the group A, respectively, and 1.26 and 1.21 in the group B,\nrespectively. In both groups, foveal CT increased significantly in high myopic patients at 2 h and at 3 months after\nsurgery, compared to preoperative values. The same tendencies were observed in the inner nasal and outer nasal\nregions..............................
Background: The measurement of the pupillary function is an indispensable test in some eye examinations, being\nnecessary the evaluation of the precision of instruments performing such measures. The aim of this study was to\nevaluate the intrasession repeatability of pupil size measurements provided by a multidiagnostic platform in a large\nsample of healthy eyes.\nMethods: This prospective study enrolled 100 healthy eyes of 100 patients, with ages ranging from 23 to 65 years\nold. Repeated pupil size measures under photopic (P, 220 lx), mesopic (M, 160 lx), low mesopic (L, 70 lx), and\nscotopic conditions (S, 1 lx) were obtained with the....................
Background: The study evaluates both functional and anatomical outcomes of retinal detachment (RD) repair by\nvitrectomy and perfluorocarbon liquid (PFCL) tamponade.\nMethods: A retrospective chart review of patients who underwent vitrectomy using PFCL tamponade for RD repair\nfrom causes such as giant tear, chronic RD, or RD with previously failed surgery.\nResults: This study included 122 eyes from 121 patients. One-hundred fourteen eyes (93.5%) had baseline vision\nworse than 20/200. The median duration of intraocular PFCL retainment was 14 days before gas or silicone oil\nreplacement. The retinal reattachment rate was 80.3%. At 1 year, the retention probability of retinal reattachment\nwas 0.84 (95% confidence interval, 0.77-0.91). Although visual improvement was found in 45.9% of patients, the\nmedian of final vision was not different between baseline and the last visit.\nConclusion: The rate of retinal reattachment operated with a short- to medium-term PFCL tamponade achieved a high\nsatisfaction rate. However, postoperative hypotony was a predictor for unfavorable visual and anatomical outcomes....
Background: This is a case of spontaneous toric implantable collamer lens (TICL) rotation that occurred twice in\nthe left eye of a patient.\nCase presentation: A 24-year-old gentleman received TICL implantation for treatment of myopic astigmatism\nencountered with spontaneous rotation of approximately........................
Background: Given the two different kinds of epiretinal membranes, this study aimed to compare both the\nstructural and functional outcomes of lamellar macular holes with and without lamellar hole-associated epiretinal\nproliferation (LHEP) after surgery.\nMethod: Publications up to July 2020 that compared the surgical outcomes of lamellar macular hole with and\nwithout LHEP were included. Forest plots were created by using a weighted summary of proportion meta-analysis.\nFixed or random effects models were used on the basis of I2 heterogeneity estimates. Meanwhile, to evaluate the\nstability of the meta-analysis, a sensitivity analysis was carried out.\nResults: Eight pertinent publications that contained a total of 176 eyes without LHEP and 173 eyes with LHEP were\nincluded.....................
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