Current Issue : July-September Volume : 2019 Issue Number : 3 Articles : 2 Articles
Anti-ageing is a key area of new product development and has grown rapidly in the eye of customers. Ageing represents accumulation of changes in a human being over time which comprises of physical, psychological and social changes. Skin ageing is a biological process which is a combination of both intrinsic and extrinsic factors. Ageing is a natural phenomenon, with time we all get visible lines on our face. It is a natural process when our face lose its youthfulness and our skin becomes thinner and drier and this type of ageing is known as intrinsic ageing. The environment and lifestyle choices cause the skin to age prematurely and this type of ageing is known as extrinsic ageing. Skin health and beauty represents well-being of a human. Many anti-ageing strategies have come up which includes procedures like transfusion of plasma from young blood, enhancement of adult neurogenesis, antioxidant intake and stem cell therapy. There are many physiological changes occurring in the body while ageing and is said to be caused by the formation of free radicals. In aged skin the loss of collagen is considered to be the characteristic histological finding. The intrinsic factors contribute to wrinkles, sagging and pigmentation issues. Nanotechnology has played a crucial role in delivering active ingredients to the skin in both patch delivery and timed release application particularly in the area of cosmetics and anti-ageing....
The aim of present work was to prepare hand sanitizer using natural antimicrobial agent and moisturizer. A clean and hygienic manufacturing environment is an essential prerequisite in order to keep contamination related reject rates low. In optimized base formulation, natural antimicrobial agents and moisturizing agent in different concentration was incorporated and subjected to various evaluation tests. Antibacterial activity of alcohol:water (65:35) and sanitizers was carried out by disk diffusion method against two human pathogenic bacteria, including Gram positive (Staphylococcus aureus) and Gram-negative bacteria (Escherichia Coli). The moisturizing activity was determined by consideration of moisture content, which was carried out with the help of Karl Fischer apparatus. Formulation containing 0.5% of carbopol was found with high viscosity hence continued the experiment by optimizing one base formulation amongst others. Zone of inhibition showed antibacterial activity with different zone of inhibition measured in mm and observed that neem extract has good antibacterial activity than ginger extract. The moisturizing activity studied by moisture content test, indicated that all the formulations were shown good moisture content with sufficient moisture content. Formulation AF2 and AF3 having good consistency and spreadability with pH in between 5.5 to 6.5. An optimized formulation AF2 and AF3 show good antibacterial activity. Hence antibacterial activity from natural sources is best alternative for the synthetic one....
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