Current Issue : April - June Volume : 2018 Issue Number : 2 Articles : 1 Articles
The present study has been aimed to prepare the diclofenac sodium tablets formulation by using banana starch and compare the banana starch and potato starch as binder, banana starch is incorporated to prevent the side effects of diclofenac like gastrointestinal problems, in addition banana starch was incorporated as binder and disintegrant which replaces normal binder used in it. Tablets prepared with potato starch were named as formulation ‘A ‘and while banana starch was in formulation ‘B’. The activity of diclofenac was not altered by banana starch verified by IR spectroscopy. The tablets were evaluated for thickness, hardness, friability, dissolution and disintegration studies. The tablet hardness, friability were generally higher with the banana starch, disintegration is slow with the banana starch tablets that indicates the sustained release of tablet and further tested for dissolution studies, which showed better release of drug. From the present study, formulation ‘B’ was found to be most effective as it decreases the side effects and the concentration of excipients....
Loading....