Current Issue : April-June Volume : 2014 Issue Number : 2 Articles : 1 Articles
Quinolines are an important class of heterocyclic compounds. Several derivatives of this class have been reported for their method of synthesis and screened for their biological activities such as antimicrobial, antimalarial, anti-inflammatory, cytotoxicity or anticancer, antibiotic, tyrokinase PDGF-RTK inhibiting agents, biofertilizing abilities and HIV-1 Integrase Inhibitors etc. The potency of these clinically useful drugs in treatment of microbial infections and other activities encouraged the development of some more potent and significant derivatives. Changes in the quinoline structure with different heterocyclic groups have offered a high degree of diversity that has proven useful for the development of new therapeutic agents having improved potency and lesser toxicity....
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