Current Issue : October-December Volume : 2012 Issue Number : 4 Articles : 1 Articles
The 2-acetyl benzimidazole was prepared by the microwave induced reaction between benzene-1, 2- diamine and lactic acid, followed by oxidation with potassium permanganate and aluminum oxide. The chalcone derivative of 2-acetyl benzimidazole was prepared by the condensation with different aldehydes and the resulting compounds were cyclized with thiourea, to get the thiazine derivatives of benzimidazole. The synthesized compounds have been characterized and confirmed by TLC, elemental analysis, IR, and 1H NMR spectroscopy and screened for their anti. Compounds containing (Cl, OH) [GR-2, GR-3] electron withdrawing groups in the substituted Benzimidazole thiazine were found to show potent antioxidant activity....
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