Current Issue : April-June Volume : 2023 Issue Number : 2 Articles : 5 Articles
Purpose: To compare a deep learning model with a radiomics model in differentiating high-grade (LR-3, LR-4, LR-5) liver imaging reporting and data system (LI-RADS) liver tumors from low-grade (LR-1, LR-2) LI-RADS tumors based on the contrast-enhanced magnetic resonance images. Methods: Magnetic resonance imaging scans of 361 suspected hepatocellular carcinoma patients were retrospectively reviewed. Lesion volume segmentation was manually performed by two radiologists, resulting in 426 lesions from the training set and 83 lesions from the test set. The radiomics model was constructed using a support vector machine (SVM) with pre-defined features, which was first selected using Chi-square test, followed by refining using binary least absolute shrinkage and selection operator (LASSO) regression. The deep learning model was established based on the DenseNet. Performance of the models was quantified by area under the receiver-operating characteristic curve (AUC), accuracy, sensitivity, specificity and F1-score. Results: A set of 8 most informative features was selected from 1049 features to train the SVM classifier. The AUCs of the radiomics model were 0.857 (95% confidence interval [CI] 0.816–0.888) for the training set and 0.879 (95% CI 0.779–0.935) for the test set. The deep learning method achieved AUCs of 0.838 (95% CI 0.799–0.871) for the training set and 0.717 (95% CI 0.601–0.814) for the test set. The performance difference between these two models was assessed by t-test, which showed the results in both training and test sets were statistically significant. Conclusion: The deep learning based model can be trained end-to-end with little extra domain knowledge, while the radiomics model requires complex feature selection. However, this process makes the radiomics model achieve better performance in this study with smaller computational cost and more potential on model interpretability....
The COVID-19 pandemic has produced social and economic changes that are still affecting our lives. The coronavirus is proinflammatory, it is replicating, and it is quickly spreading. The most affected organ is the lung, and the evolution of the disease can degenerate very rapidly from the early phase, also known as mild to moderate and even severe stages, where the percentage of recovered patients is very low. Therefore, a fast and automatic method to detect the disease stages for patients who underwent a computer tomography investigation can improve the clinical protocol. Transfer learning is used do tackle this issue, mainly by decreasing the computational time. The dataset is composed of images from public databases from 118 patients and new data from 55 patients collected during the COVID-19 spread in Romania in the spring of 2020. Even if the disease detection by the computerized tomography scans was studied using deep learning algorithms, to our knowledge, there are no studies related to the multiclass classification of the images into pulmonary damage stages. This could be helpful for physicians to automatically establish the disease severity and decide on the proper treatment for patients and any special surveillance, if needed. An evaluation study was completed by considering six different pre-trained CNNs. The results are encouraging, assuring an accuracy of around 87%. The clinical impact is still huge, even if the disease spread and severity are currently diminished....
Machine learning is the leading field of artificial intelligence that has achieved expert-level performance. Diagnosis and treatment of various medical diseases have led to advancements in medical imaging. Chest X-ray-based thoracic disease classification or identification is one of the potential applications in medical imaging based on machine learning. The study consists of 112,120 images of 30,804 individual patients with fourteen thoracic disease labels, which encapsulated the support vector machine (SVM). We have considered 04 kernels in SVM, namely, linear (L-SVM), polynomial (P-SVM), radial basis (R-SVM), and hyperbolic tangent (H-SVM) for classification of thoracic diseases based on X-ray images. To reduce the dimensionality and outliers from the SVM, variants are coupled with novel fast principal component analysis (FPCA). It appears that there is a significant (p ≤ 0.05) difference between SVM variants where P-SVM and R-SVM next in order outperforms on most of the disease identification models with average validated classification accuracy ranging from 92% to 98%. The average calibrated accuracy ranges from 99.5% and reaches to 100% in most of the cases. The study is worth investigating as it is good for radiologists as they will be able to classify the diseases and it will help in improving and enhancing different medical techniques....
In this era of pandemic, the future of healthcare industry has never been more exciting. Artificial intelligence and machine learning (AI & ML) present opportunities to develop solutions that cater for very specific needs within the industry. Deep learning in healthcare had become incredibly powerful for supporting clinics and in transforming patient care in general. Deep learning is increasingly being applied for the detection of clinically important features in the images beyond what can be perceived by the naked human eye. Chest X-ray images are one of the most common clinical method for diagnosing a number of diseases such as pneumonia, lung cancer and many other abnormalities like lesions and fractures. Proper diagnosis of a disease from X-ray images is often challenging task for even expert radiologists and there is a growing need for computerized support systems due to the large amount of information encoded in X-Ray images. The goal of this paper is to develop a lightweight solution to detect 14 different chest conditions from an X ray image. Given an X-ray image as input, our classifier outputs a label vector indicating which of 14 disease classes does the image fall into. Along with the image features, we are also going to use non-image features available in the data such as X-ray view type, age, gender etc. The original study conducted Stanford ML Group is our base line. Original study focuses on predicting 5 diseases. Our aim is to improve upon previous work, expand prediction to 14 diseases and provide insight for future chest radiography research....
In clinical applications, the classification of ultrasound images needs to be processed as an aid to diagnosis. Based on this, a hybrid model of cascaded deep convolutional neural network consisting of two different CNNs and a new classification method are designed and evaluated for its feasibility and effectiveness in ultrasound image classification. A total of 1000 pathological slides of patients with thyroid nodular lesions kept in the Department of Pathology of the First Affiliated Hospital of Lanzhou University, China, were retrospectively collected. After image acquisition, the images were randomly divided into training set, validation set, and test set in the ratio of 4 : 3 : 3. Three convolutional neural network models (VGG 19 model, Inception V3 model, and DenseNet 161 model) with pretraining parameters acquired on the training set were trained, and the models were combined to construct an integrated learning model, and the performance of the models in recognizing pathological images was evaluated based on the test set data.Theexperimental results show that the VGG 19 model is less effective in classification, with a correct rate of 88.20%, which is lower than that of Inception V3 and DenseNet161 models (92.87% and 92.95%). InceptionV3 and DenseNet161 models have significant advantages in terms of accuracy, number of parameters, and training efficiency, where the DenseNet161 model has faster convergence and better generalization performance, but occupies more video memory in the operation; moreover, the DenseNet161 operation time (1986.48 s) and response time (16 s) are better than the other two models. In addition, the integrated learning of InceptionV3 and DenseNet161 can improve the recognition of pathological images by a single model. Compared with other methods, the performance of the cascaded CNNs proposed in this study is significantly improved, and the multiview strategy can improve the performance of cascaded CNNs. The experimental results demonstrate the potential clinical application of cascaded CNNs, which can provide physicians with an objective second opinion and reduce their heavy workload, in addition to making the diagnosis of thyroid nodules easy and reproducible for people without medical expertise....
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