Current Issue : July-September
Volume : 2020
Issue Number : 3
Articles : 1 Articles
Eczema or Atopic Dermatitis (AD) is an inflammatory skin condition which mostly affects children and also adults. Eczema is most commonly associated with other immunologic disorders like asthma and allergic rhinitis. The genetic risk factor for atopic dermatitis is mutation of filaggrin gene positioned in chromosome 1, which give rise to functional impairments in the filaggrin protein and there by disrupt the skin barrier. A higher incidence of eczema is associated with urban and industrial settings, higher socioeconomic status and smaller family size. The pathogenesis involves both the adaptive and innate immune systems and barrier dysfunctions. The treatment aims to minimize the number of exacerbations of the flares, reduce the duration and degree of the flare, if flare occurs; skin hydration is a key component in the management, such that emollient, topical corticosteroids, topical antibacterials, topical immunosuppressants, antiallergic and antihistamines, topical calcineurine inhibitors, coal tar and UV therapy are used....
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