Inventi Impact - Advanced Dosaging
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Advanced Dosaging’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. This journal focuses on finding the newer methods of administering active pharmaceuticals to the patients either through newer dosage forms of by deploying newer administration devices. The first of its kind of journal, ‘Inventi Rapid/Impact: Advanced Dosaging’ invites researchers sharing new insight in achieving the therapeutic goals.
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FOCUS ON MAGNETIC DRUG DELIVERY SYSTEM OPTIMIZATION AND SAFETY ASPECTS OF TABLET DOSAGE FORM USING ANTICANCER DRUG IMATINIB MESYLATE
The primary focus of this study was to highlight the impact of magnetite particles on systemic circulation. Magnetite which is a magnetic component used in magnetic targeted system composition, revealed absorption and its appearance in systemic circulation showcased through changes in the heamogram. Tablet dosage form based on the magnetic drug delivery concepts was developed successfully using mo...
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OPTIMIZATION AND CHARACTERIZATION OF RIFAMPICIN LOADED RESEALED ERYTHROCYTE: IN-VITRO AND IN-VIVO STUDIES
Resealed erythrocyte loaded antiviral agent have potential effective therapy against modified tuberculosis pathogens. The advantages over the administration of rifampicin, includes less dose, decreased toxicity and lower systemic dose which can produce sustained delivery of the rifampicin at peak concentration to the intracellular site of microbial replication and increased therapeutic efficacy...
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HIGH DOSE INSULIN THERAPY, AN EVIDENCE BASED APPROACH TO BETA BLOCKER/CALCIUM CHANNEL BLOCKER TOXICITY
Poison-induced cardiogenic shock (PICS) as a result of beta-blocker (ß-blocker) or calcium channel blocker (CCB) overdose is a common and potentially life-threatening condition. Conventional therapies, including fluid resuscitation, atropine, cardiac pacing, calcium, glucagon, and vasopressors often fail to improve hemodynamic status. High-dose insulin (HDI) is an emerging therapeutic modality fo...
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FLUOXETINE DOSE AND ADMINISTRATION METHOD DIFFERENTIALLY AFFECT HIPPOCAMPAL PLASTICITY IN ADULT FEMALE RATS
Selective serotonin reuptake inhibitor medications are one of the most common treatments for mood disorders. In humans, these medications are taken orally, usually once per day. Unfortunately, administration of antidepressant medications in rodent models is often through injection, oral gavage, or minipump implant, all relatively stressful procedures. The aim of the present study was to investigat...
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EFFICACY OF A LOW DOSE OF ESTROGEN ON ANTIOXIDANT DEFENSES AND HEART RATE VARIABILITY
This study tested whether a low dose (40% less than the pharmacological dose of 17-?? estradiol) would be as effective as the pharmacological dose to improve cardiovascular parameters and decrease cardiac oxidative stress. Female Wistar rats (?? = 9/group) were divided in three groups: (1) ovariectomized (Ovx), (2) ovariectomized animals treated for 21 days with low dose (LE; 0.2mg), and (3) high ...
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LOW DOSE OF VALPROATE IMPROVES MOTOR FUNCTION AFTER TRAUMATIC BRAIN INJURY
Background. Traumatic brain injuries (TBIs) are a major health care problem worldwide. Approximately 1.5 million new TBI cases occur annually in the United States, with mortality rates ranging between 35% and 40% in severe patients. Despite the incidence of these injuries and their substantial socioeconomic implications, no specific pharmacological intervention is available for clinical use. Sever...
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