Current Issue : April - June Volume : 2021 Issue Number : 2 Articles : 7 Articles
Background. Cystic fibrosis (CF) is one of the most frequent genetic diseases. )e discovery and implementation of new therapies\nprolonged the survival of CF patients in the last years. Evaluation of long-term complications could be useful to improve the\noutcome of these patients. Aim of the Study. To evaluate renal function, metabolic, nutritional, and inflammatory status in CF\npatients on cystic fibrosis transmembrane regulator (CFTR) modulators therapy as well as lung transplant recipients (LRs) and\npatients on conservative therapy (control group). Materials and Methods. We performed a prospective, longitudinal study on 69\nCF patients....
Airway complications after lung transplantation are a major cause of morbidity and mortality. Bronchial dehiscence presents\nwithin a month of lung transplantation and is typically diagnosed radiographically as a sentinel gas pocket at the anastomotic\nsite and confirmed with bronchoscopy. A 66-year-old man with idiopathic pulmonary fibrosis who underwent a right lung\ntransplantation 4 weeks prior developed chest pain with palpable crepitus over his right chest wall. A chest X-ray revealed\nsubcutaneous emphysema and a small right-sided pneumothorax. Computed tomography (CT) of the thorax without contrast\nrevealed a gas pocket at the anastomotic site in the mediastinum as well as interstitial emphysema around the proximal bronchi\nof the right lung that had worsened when compared to CT from 11 days prior. A review of prior CT demonstrated interstitial\nemphysema without evidence of a sentinel gas pocket....
Background. Renal transplant has emerged as a preferred treatment modality in cases of end-stage renal disease; however, a small\npercentage of cases suffer from graft dysfunction. Aim. To evaluate the renal transplant biopsies and analyze the various causes of\ngraft dysfunction. Materials and Methods. 163 renal transplant biopsies, reported between 2014 and 2019 and who fulfilled the\ninclusion criteria, were evaluated with respect to demographics, clinical, histological, and immunohistochemical features. Results....
Background. Perioperative and follow-up outcomes for patients that received robot-assisted kidney transplant (RAKT), compared\nto patients that received conventional open kidney transplant (OKT), remain unknown. We performed a meta-analysis of\ncontrolled studies to compare the safety and efficacy of RAKT versus OKT. Methods. Systematic searching of PubMed,\nEmbase, and Cochrane Library databases was performed to identify relevant randomized or nonrandomized controlled\nstudies. Perioperative, in-hospital, and follow-up outcomes were summarized. A random-effect model incorporating the\npotential heterogeneity was used to synthesize the results. Results....
Background. Lophomonas blattarum is a flagellate protozoan which is known as an emerging parasite in the human respiratory\nsystem. Organ transplant recipients are considered as immunocompromised patients due to prescription of immunosuppressive\ndrugs. -is group of patients is susceptible to opportunistic infection as well as lophomoniasis. -is study aims to investigate the\nprevalence and clinical manifestation of pulmonary infections caused by L. blattarum in kidney transplant recipients. Methods.\n-is is a case-control study including 50 kidney transplant recipients and 50 controls....
Macular hole retinal detachment (MHRD) for the most part develops in highly myopic eyes. Several surgical methods have been\nintroduced to treat MHRD. We describe our experience with the autologous retinal transplant in patient with MHRD. A 49-yearold\nfemale presented with a 2-week history of a sudden decrease in the central vision in the right eye (RE). A 3-port, 25-gauge\npars plana vitrectomy was performed with the ILM dye staining and peeling. Endodiathermy was applied around a 1.5-disc\ndiameter neurosensory donor site in the supertemporal retina. The graft was cut with standard 25-gauge curved scissors.\nPerfluoro-n-octane (PFO) was instilled. The free graft was gently handled until its packing into the macular hole. Two months\nfollowing the initial PPV, the macular hole was closed, and vision improved from 0.05 to 0.25 logMAR....
Background. Therapy with direct-acting antivirals (DAA) for HCV is safe and effective in the liver (LT) and kidney transplant (KT)\nrecipients; however, data on the quality of life (QoL) of patients are scanty. This pilot study is aimed at prospectively evaluating the\nQoL in LT and KT recipients before and after DAA treatment. Methods. We prospectively enrolled 17 LT and 11 KT recipients with\nHCV infection starting a sofosbuvir-based antiviral therapy for 12 weeks. All participants before (T0), 12 (T12), and 24 (T24) weeks\nafter the end of the therapy completed the Short Form Health Survey (SF-36) questionnaire, the Zung Self-rating Depression Scale,\nand State-Trait Anxiety Inventory (STAIâ??Y1â??Y2). Results. At T0, LT and KT patients were similar for gender, age, BMI, smoking\nhabits, marital status...
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