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Inventi Impact - Pharm Tech

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Tech’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutics and pharmaceutical technology. It welcomes articles pertaining to physical, chemical and biological properties of dosage forms, devices and delivery systems for drugs, vaccines and biologicals including their design, manufacture and evaluation. Special emphasis is given for articles pertaining to excipients such as surfactants and polymers and novel materials, and products for personalized medication.

  • FORMULATION AND CHARACTERIZATION OF ATORVASTATIN CALCIUM LIPOSOMES
    Bhot V D, Dangat M R, Mahajan K C, Gawade A S    Download Full Text

    Present study investigated most efficient technique for the development of atorvastatin calcium liposomes. Aorvastatin calcium is a HMG-Co reductase inhibitor widely used in the treatment or prevention of hypercholesterolemia, mixed hyperlipidemia, coronary heart disease or stroke. Our work is mainly focused on in-vitro studies of liposomal formulation encapsulated with atorvastatin calcium which ...

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  • FORMULATION AND EVALUATION OF PRESS COATED TABLETS OF MESALAMINE
    Naseeb Basha Shaik*, Sravani P, Latha Kukati, Mobina Begum    Download Full Text

    Mesalamine an anti-inflammatory drug, which degrades in acidic environment. Hence protection of drug is done by coating the drug with retardant coating polymers. The aim and objective of the present study was to prepare press coated tablets of mesalamine by press coating technique. Core tablets were prepared by direct compression method and evaluated for their physicochemical properties. Formulati...

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  • DESIGN AND DEVELOPMENT OF PALIPERIDONE LIQUISOLID COMPACTS TO ENHANCE SOLUBILITY
    K Arshad Ahmed Khan*, A Aswini, B Srinath, C Suryaprakash Reddy    Download Full Text

    Paliperidone is a second generation antipsychotic agent, used in the treatment of schizophrenia. It is a hydrophobic drug which belongs to BCS class II and it has low bioavailability of about 28%. The present study was designed to improve the in-vitro dissolution properties of poorly soluble antipsychotic drug paliperidone by adopting the liquisolid technology. Liquisolids were prepared by powder ...

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  • FORMULATION AND EVALUATION OF MONTELUKAST SODIUM FAST DISSOLVING TABLETS
    Shiva Kumar Yellanki*, Teelavath Mangilal, M Sushanth    Download Full Text

    The demand for fast dissolving tablet (FDT) has been growing during the last decade especially for elderly people and children who have swallowing difficulties. Montelukast is a leukotriene receptor antagonist (LTRA), anti-asthmatic used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. It is effective in relieving nasal congestion, particularly in patients wit...

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  • PLEASANT TASTING GRANULES OF CLARITHROMYCIN
    Yitesh Jagwani*, Siddhraj S Sisodia    Download Full Text

    Clarithromycin has poor acceptance by pediatric and geriatric patients due to very bitter taste. Usually, in dry syrup formulations, high concentration of sugar is used for taste masking purpose. But high consumption of sugar has been related to several chronic diseases and several times is unable to mask the extreme bitter taste. Therefore this study aimed to investigate taste masking capacity of...

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  • EFFECT OF PH ON THE EFFICACY OF THE SODIUM BENZOATE AS ANTIMICROBIAL PRESERVATIVE IN TOPICAL FORMULATION
    Shelke Om*, Kulkarni Amol    Download Full Text

    Preservatives are used to maintain the microbiological attributes of the formulation throughout the shelf life. Sodium benzoate is used as preservative in oral, parenteral and topical formulations. Antimicrobial effectiveness testing (AET) was carried out using different concentration of sodium benzoate at different pH levels. Bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureu...

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