Inventi Impact - NDDS
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: NDDS’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under novel drug delivery systems. It welcomes articles pertaining to nano drug delivery systems; gastroretensive system, colonic drug delivery, bioadhesive and mucoadhesive systems; nasopulmonary drug delivery; ocular delivery; transdermal delivery, implants and inserts; protein and peptide delivery; manufacturing, quality control and regulatory aspects of NDDS, etc.
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BISOPROLOL HEMIFUMARATE MATRIX TABLETS FOR SUSTAINED RELEASE: PREPARATION AND EVALUATION
Bisoprolol hemifumarate is a selective beta-1-blocker used in the treatment of coronary heart failure. It is characterized by being freely water soluble. Very limited trials were developed to prepare sustained release dosage forms of this drug. In this work, bisoprolol hemifumarate formulated as matrix tablets containing 20 mg of the drug so as to extend its release over a period of more than five...
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SYNTHESIS AND CHARACTERIZATION OF SILVER NANOPARTICLES USING SESBANIA GUM POWDER
This research presented a novel as well as an easy method for a green synthesis of silver nanoparticles (AgNPs) using autoclave assisted gum extract of sesbania gum. Silver nanoparticles were formed due to the reduction of silver nitrate solution when mixed with the gum extract after autoclaving at 121°C and 15 psi. The water soluble components in the gum act as reductants and stabilizers. The ge...
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DEVELOPMENT AND OPTIMIZATION OF SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM FOR BOSENTAN MONOHYDRATE BY D-OPTIMAL MIXTURE DESIGN: IN-VITRO AND IN-VIVO EVALUATION
The aim of the present study was to develop and optimize the self-microemulsifying drug delivery formulation of bosentan monohydrate (BM) and assess the pharmacokinetic parameters in rats. Poor aqueous solubility of bosentan monohydrate (BM) is a major determinant of its low oral bioavailability. Screening of various components of SMEDDS was done by solubility study. Clove oil as oil, tween 80 and...
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FORMULATION AND EVALUATION OF STOMACH SPECIFIC CHITOSAN BASED MUCOADHESIVE MICROSPHERES OF METOPROLOL TARTRATE BY SPRAY DRYING
The objective of this research work was to formulate and evaluate of stomach specific chitosan based mucoadhesive microspheres of metoprolol tartrate by spray drying. The main drawbacks of metoprolol tartrate conventional dosage formulation are short biological half-life, its selective absorption form upper part of gastrointestinal tract, frequent administration and low oral bioavailability. By pr...
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DESIGN AND CHARACTERIZATION OF HPMC MINI-TABLETS CAPSULE CONTAINING ATORVASTATIN
Mini-tablets are a great alternative for pellets and granules, because of their relative ease of manufacturing and dosage forms of equal dimensions, weight with smooth regular surface can be produced in a reproducible and continuous way. The main objective of the study was to develop and to evaluate encapsulated mini-tablets systems, in order to achieve desired target product profile for extended ...
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FORMULATION AND CHARACTERIZATION OF NYSTATIN LOADED LIQUID CRYSTALLINE GEL
Nystatin (NT) is an antibiotic which shows both fungistatic and fungicidal activity against a wide variety of yeasts and yeast-like fungi, including Candida albicans. Nystatins have very low permeation topically. NT also shows skin irritation by topical application. Thus the aim of present study was to increase solubility, permeability of NT and also reduce skin irritation by formulating a lyotrop...
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