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Inventi Impact - NDDS

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: NDDS’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under novel drug delivery systems. It welcomes articles pertaining to nano drug delivery systems; gastroretensive system, colonic drug delivery, bioadhesive and mucoadhesive systems; nasopulmonary drug delivery; ocular delivery; transdermal delivery, implants and inserts; protein and peptide delivery; manufacturing, quality control and regulatory aspects of NDDS, etc.

  • MEFENAMIC ACID FAST DISINTEGRATING TABLET FORMULATION BY SUBLIMATION METHOD AND ITS EVALUATION
    Prasad M S*, Somashekhar C N, Senthilkumar G P    Download Full Text

    Mefenamic acid fast disintegrating tablets were formulated by using sublimation method to reduce the bitter taste and first pass hepatic metabolism with a view to enhance patient compliance. Three different superdisintegrants viz., crospovidone, croscarmellose sodium and sodium starch glycolate were used in different ratios (6% and 12%) along with camphor, beta cyclodextrin, microcrystalline cellu...

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  • PH TRIGGERING OPHTHALMIC IN-SITU GEL OF AZITHROMYCIN FOR THE TREATMENT OF CONJUNCTIVITIS
    Rashmi B*, Somashekhar C N    Download Full Text

    The intensive research is implemented within the ophthalmic drug delivery system to attain the far better drug products. For the treatment of eye alignment one amongst the foremost promising route of drug delivery is ophthalmic route. Within the modern pharmaceutical design controlled and sustained drug delivery has become the standard in order to overcome the problem related with the conventional...

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  • FORMULATION, OPTIMIZATION AND IN-VITRO EVALUATION OF FELODIPINE LOADED ETHOSOMES
    Sinar Sayed, Nihal Farid Younes    Download Full Text

    The purpose of this work was to develop felodipine-loaded ethosomes to advance its therapeutic efficacy through transdermal delivery. Ethosomes (ES) were fabricated via a 31.21 mixed full factorial design, the factors considered were; phospholipid amount (200 mg and 300 mg), Felodipine amount (10 mg and 20 mg) and ethanol percentage (10% and 15 % v/v). All ethosomes were formulated with thin-film ...

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  • FORMULATION AND CHARACTERIZATION OF SUSTAINED RELEASE MULTIPARTICULATE GASTRORETENTIVE DOSAGE FORM OF BACLOFEN
    Pratik P Patil*, Padmini Ravikumar, Aparajita Varshneya    Download Full Text

    The objective of the study was to formulate and evaluate once daily, multiparticulate gastroretentive dosage form of baclofen for achieving sustained drug release, reducing side effects and frequency of administration leading to improved patient compliance. Gastroretention was achieved by designing multilayered effervescent pellets using extrusion spheronization technique. The pellet core containe...

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  • DEVELOPMENT AND EVALUATION OF THIOCOLCHICOSIDE LOADED MICROSPHERES
    More Rutuja K, Patil Moreshwar P, Dhivare Karishma M*, Borase Prashant J, Kshirsagar Sanjay J    Download Full Text

    Thiocolchicoside is a semi synthetic drug derived from colchicoside used as a muscle relaxant as well as an anti-inflammatory agent. It has high aqueous solubility and low bioavailability. Hence, the aim of this study was to prolong the release of thiocolchicoside by developing polymeric microspheres. Microspheres were produced by ionotropic gelation technique to prolong the release of thiocolchic...

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  • FORMULATION AND EVALUATION OF SERTACONAZOLE NITRATE MICROSPONGE GEL
    Mutha Rakesh Eshwarlal, Chatap Vivekanand Kishan, Patil Vijay Krishnarao, Chachare Harshala Motiram*    Download Full Text

    In the present study, controlled release sertaconazole nitrate (SZN) microsponge gel for topical delivery was formulated and evaluated. Microsponges were prepared successfully using six different proportions of ethyl cellulose as a polymer, using PVA as surfactant by the quasi-emulsion solvent diffusion method. The influence of the drug to polymer ratio, surfactant concentration, inner phase volum...

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