Inventi Impact - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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DEVELOPMENT AND VALIDATION OF LIQUID CHROMATOGRAPHIC METHOD FOR ESTIMATION OF DARIFENACIN HYDROBROMIDE IN LIPOSOMES
A simple and sensitive liquid chromatographic method was developed for the estimation of darifenacin hydrobromide in liposomes. Analysis was carried out on Enable 18H C18 column using a mobile phase consisting of phosphate buffer pH 3 and acetonitrile (60:40 %v/v). The mobile phase was pumped at a flow rate of 1 ml/min and UV-detection was carried out at 284 nm. Linearity was observed over concent...
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ANALYTICAL METHOD DEVELOPMENT AND INVESTIGATION OF CAFFEINE CONTENT FROM COFFEA ARABICA AND ANTI-OBESITY FORMULATION AS PER ICH Q2 (R1) PROTOCOL OF VALIDATION
Precise and sophisticated HPTLC and HPLC methods were developed for determination of caffeine from coffee bean extract. HPTLC analysis was performed on silica gel 60 F254 plate using ethyl acetate: methanol: water in the proportion of 10: 1.4: 1 (v/v/v) as mobile phase. A clear band of caffeine was observed at Rf value 0.55 (+0.1). Caffeine shows linearity within the concentration range of 200-600...
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SIMULTANEOUS ESTIMATION OF RIBOCICLIB AND PALBOCICLIB IN BULK SAMPLES BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
This work concerns with the development and validation of a simple, specific and cost effective RP-HPLC method for simultaneous estimation of ribociclib and palbociclib in bulk samples. Chromatography was carried on Kromasil C18 column with mobile phase comprising of 20 mM phosphate buffer (pH-5): methanol: acetonitrile (40:30:30, v/v/v). The flow rate was adjusted to 1 ml/min with PDA detection a...
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FIRST ORDER DERIVATIVE AND AREA UNDER CURVE UV SPECTROSCOPIC METHODS FOR THE ESTIMATION OF CYAMEMAZINE TARTRATE IN BULK AND ITS PHARMACEUTICAL DOSAGE FORM
The present research work focused on development and validation of first order derivative and area under curve (AUC) UV spectroscopic method for the estimation of cyamemazine tartrate in bulk and its pharmaceutical dosage form. The solutions of standard and sample solutions were prepared by ethanol. The calibration curve was observed in the concentration range of 2-12 Micro g/ml for both methods. ...
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DEVELOPMENT AND VALIDATION OF VISIBLE SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVE ESTIMATION OF MESALAMINE IN BULK AND DOSAGE FORMS
The aim of the study was to develop and validate a visible spectrophotometric method for the quantitative estimation of mesalamine in pure form and in formulations i.e. in tablets and suppositories. 0.1N HCl selected as solvent, 0.5 ml of 0.5% MBTH used as chromogenic reagent and 2 ml of 1% cerric ammonium sulphate solution was added as oxidizing agent to develop the color. The intensity of the de...
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RP-HPLC METHOD DEVELOPMENT FOR THE DETERMINATION OF RIZATRIPTAN BENZOATE IN BULK DRUG AND TABLET DOSAGE FORM
A simple, rapid, accurate, precise and reproducible RP-HPLC method for the estimation of rizatriptan benzoate in bulk and tablet dosage form was developed and validated as per ICH guidelines. The separation was done using Enable C18 G 150 x 4.6 mm, 5μ column. The mobile phase (water and methanol; 80:20% v/v) was pumped at 1.0 ml/min and effluent was detected at 225 nm using a PDA detector. The ...
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