Inventi Impact - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF OFLOXACIN IN BULK AND TABLET DOSAGE FORM USING AREA UNDER CURVE METHOD
A simple, precise, accurate and economical UV visible spectrophotometric method has been developed for estimation of ofloxacin drug by AUC method. The standard and sample solutions were prepared by using double distilled water as a solvent. Quantitative determination of the drug was performed at wavelength range 276-300 nm. The linearity was established over the concentration range of 02-10 μg/ml...
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SIMULTANEOUS ESTIMATION OF METOPROLOL SUCCINATE AND CHLORTHALIDONE IN PHARMACEUTICAL SOLID DOSAGE FORM BY USING A DEVELOPED AND VALIDATED HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC TECHNIQUE
This work represents development and validation of novel, accurate, precise, rugged, robust and reproducible high performance thin-layer chromatographic technique for the simultaneous estimation of metoprolol succinate and chlorthalidone from marketed formulation. High performance thin-layer chromatography was performed using HPTLC aluminium plates precoated silica gel plate 60 F254 as stationary ...
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QUANTITATIVE DETERMINATION OF β-POLYMORPHIC FORM IN IMATINIB MESYLATE α-POLYMORPHIC FORM OF TABLET FORMULATION USING CALIBRATION CURVE METHOD BY USING POWDER X-RAY DIFFRACTION (PXRD) AND DIFFERENTIAL SCANNING CALORIMETRY (DSC)
Imatinib mesylate exhibits many polymorphic forms and most stable and commercialized polymorphs are α and β forms. Molecules in α and β polymorphic forms exhibit significant conformational differences due to their different intra- and intermolecular interactions, which stabilize their molecular conformations and affect their physicochemical properties such as bulk density, melting point, solub...
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SIMULTANEOUS ESTIMATION OF MEFENAMIC ACID AND TIZANIDINE IN TABLET DOSAGE FORM BY DUAL WAVELENGTH METHOD
In the present work one simple and sensitive UV spectrophotometric method have been developed for the quantitative estimation of mefenamic acid and tizanidine hydrochloride in combination. For this dual wavelength method, 222 nm and 237 nm were selected as λ1 and λ2 for the determination of mefenamic acid and 240 nm and 272 nm were selected as λ3 and λ4 for the determination of tizanidine hydr...
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CHIRAL SEPARATION OF OFLOXACIN RACEMATE USING LIGAND EXCHANGE CHROMATOGRAPHY
The chiral separation of ofloxacin racemate by ligand exchange chromatography was studied and method was developed. A kromstar ODS column was used with the mobile phase consisting of a methanol–water solution (containing different concentrations of L-isoleucine and copper sulfate as chiral mobile phase additives) at flow rate of 1 ml/min. The effect of different mobile phase parameters such as c...
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NOVEL UV SPECTROPHOTOMETRIC AND RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF GLIMEPIRIDE IN BULK AND PHARMACEUTICAL FORMULATION
Two simple, precise and easy methods were successfully developed for the estimation of glimepiride in bulk and pharmaceutical dosage forms. The first method was based on UV-spectrophotometry, which is linear in the concentration range of 3-18 μg/ml at maximum absorbance (λ max) 228.4 nm. The correlation coefficient was found to be 0.9998. The accuracy of the method was ranged from 100.20 to 101....
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