Inventi Impact - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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FIRST ORDER DERIVATIVE AND AREA UNDER CURVE UV SPECTROSCOPIC METHODS FOR THE ESTIMATION OF CYAMEMAZINE TARTRATE IN BULK AND ITS PHARMACEUTICAL DOSAGE FORM
The present research work focused on development and validation of first order derivative and area under curve (AUC) UV spectroscopic method for the estimation of cyamemazine tartrate in bulk and its pharmaceutical dosage form. The solutions of standard and sample solutions were prepared by ethanol. The calibration curve was observed in the concentration range of 2-12 Micro g/ml for both methods. ...
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DEVELOPMENT AND VALIDATION OF VISIBLE SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVE ESTIMATION OF MESALAMINE IN BULK AND DOSAGE FORMS
The aim of the study was to develop and validate a visible spectrophotometric method for the quantitative estimation of mesalamine in pure form and in formulations i.e. in tablets and suppositories. 0.1N HCl selected as solvent, 0.5 ml of 0.5% MBTH used as chromogenic reagent and 2 ml of 1% cerric ammonium sulphate solution was added as oxidizing agent to develop the color. The intensity of the de...
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RP-HPLC METHOD DEVELOPMENT FOR THE DETERMINATION OF RIZATRIPTAN BENZOATE IN BULK DRUG AND TABLET DOSAGE FORM
A simple, rapid, accurate, precise and reproducible RP-HPLC method for the estimation of rizatriptan benzoate in bulk and tablet dosage form was developed and validated as per ICH guidelines. The separation was done using Enable C18 G 150 x 4.6 mm, 5μ column. The mobile phase (water and methanol; 80:20% v/v) was pumped at 1.0 ml/min and effluent was detected at 225 nm using a PDA detector. The ...
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DEGRADATION KINETIC STUDY OF DIFLUPREDNATE BY USING VALIDATED STABILITY-INDICATING LIQUID CHROMATOGRAPHIC METHOD
The objective of this investigation was to study the degradation behavior and kinetics of the difluprednate from ophthalmic emulsion under different ICH recommended stress condition by validated stability indicating LC method for quantification of potential known and unknown degradation product. Chromatographic separation was achieved on the C-18 stationary phase with a gradient elution using a mo...
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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF MONTELUKAST AND RUPATADINE IN PHARMACEUTICAL DOSAGE FORM
The aim of the present study was the development and validation of a simple, precise and specific RP-HPLC method for assay of montelukast (MNT) and rupatadine (RPT) in tablet dosage forms. The separation was achieved on Grace C-18 Column (4.6 × 250 mm, 5 μm) using acetonitrile and 0.05% OPA (60:40, v/v) as mobile phase for assay, flow rate 1 ml/ min and detection was carried out in U.V dete...
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SIMULTANEOUS ESTIMATION OF BACOSIDE A3, PIPERINE AND CROCIN IN POLYHERBAL FORMULATION BY CHEMOMETRIC ASSISTED RP-HPLC METHOD
A simple RP-HPLC method was developed and chemometric designs were applied for the simultaneous estimation of bacoside A3 (BA3), piperine (PPN) and crocin (CON) in polyherbal formulation brahmi vati. The separation was carried out by using phenomenex C18 column (15 cm • 4.6 mm id, 5 μm particle size). For the optimization the ranges of independent variables used were MeCN: 33–38%, ...
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