Inventi Impact - Pharm Biotech & Microbio
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Biotech & Microbio’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. This journal focuses on methods, applications and findings in pharmaceutical microbiology and biotechnology. Papers from all relevant areas such as antimicrobial studies, tissue culture technology, gene methods, enzyme technology, recombinant DNA technology, antibiotics screening and production are invited.
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ANTIMICROBIAL ACTIVITY OF ISOLATED ACTINOMYCETES AND OPTIMIZATION OF BIOACTIVE METABOLITES PRODUCTION
The objective of this research was to screen, select and isolate actinomycetes from 10 salty soil samples. The ability of the isolated strains to produce antimicrobials metabolites was evaluated against pathogenic strains: Escherichia coli, Staphylococcus aerus and Candida albicans by using disc diffusion agar plate technique. Optimization of the production of bioactive metabolites from the most p...
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PREPARATION OF A MORE STABLE LYOPHILIZED BCG-T WITH THE SAME BIOPOTENTIAL FOR BLADDER CANCER IMMUNOTHERAPY
BCG-T is a new trend for immunotherapy of bladder cancer as an alternative to chemotherapy. The available product is liquid form of a limited stability profile. The present study aims to prepare a lyophilized form of BCG-T using different stabilizer namely Na glutamate and lactose. Stability of pharmaceutical lyophilized injection dosage form compared with the liquid form was assessed revealing th...
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PRODUCTION OF CHITOOLIGOSACCHARIDES BY DOTHIDEOMYCETES SP. CSS035 CHITOSANASE
Dothideomycetes sp. Css035 was used for the production of chitosanase with specific activity 3.41 U/mg that have been increased by 2.45 fold by the use of 30-70% ethanol concentration as a precipitating agent. The optimal conditions for enzymatic hydrolysis of chitosan was found to be, the addition of chitosanase with enzyme/ substrate ratio 0.05 U/mg to 2 ml of 2% soluble chitosan in a shaking wa...
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TO STUDY THE EFFECT OF ANTIBIOTICS ON NUTRITIVE VALUES OF PROBIOTIC CURD AND LACTOBACILLUS PLANTARUM FORTIFIED PROBIOTIC CURD
Probiotic curd (PC) is an identical food product that supplies live bacterial strains and additive fibers to the human body to maintain normal gut function and digestion. One objective of this study was to determine various nutritive value parameters such as protein content, total carbohydrates, reducing sugar, organic acids, ascorbic acid/Vitamin-C, anti-oxidant activity, total phenolic content a...
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EVALUATION OF CULTURE CONDITIONS FOR CHITOSANASE PRODUCTION BY DOTHIDEOMYCETES SP. CSS035
The aim of this research was to find a new microbial source for chitosanase production. Optimization of the fermentation conditions and medium compositions to maximize the enzyme production was studied by using one variable at a time technique, characterization of the crude enzyme as well as studying the ability of this enzyme to produce chitooligosaccharides from chitosan at different times that ...
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ANTIMICROBIAL ACTIVITIES OF JELLYFISH, PORPITA PORPITA FROM SOUTHEAST COAST OF INDIA
Antibacterial and antifungal activity of ethanol, methanol, chloroform and diethyl ester extract of dried jellyfish (Porpita porpita) was assayed against five gram-ve (Klebsiella pneumoniae, Pseudomonas sp., Vibrio cholerae, Streptococcus pyrogenes and Escherichia coli) and five gram+ve bacteria (Staphylococcus aureus, Bacillus sp., Enterococcus sp., Clostridium sp., Nocardia sp.). The antifungal ...
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