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Inventi Rapid - Pharm Tech

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Tech’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutics and pharmaceutical technology. It welcomes articles pertaining to physical, chemical and biological properties of dosage forms, devices and delivery systems for drugs, vaccines and biologicals including their design, manufacture and evaluation. Special emphasis is given for articles pertaining to excipients such as surfactants and polymers and novel materials, and products for personalized medication.

  • FORMULATION AND DEVELOPMENT OF TELMISARTAN ORAL FAST DISSOLVING FILMS
    S Naga Jyothi, Y Swetha, M Lakshmi Swapna Sai*, Gulshan Mohammad, Rama Rao Nadendla    Download Full Text

    The oral mucosa is vascularized whereby absorbed drugs get direct access to the systemic circulation without first pass metabolism. Taking this advantage the present work is to formulate mouth dissolving film of telmisartan for enhanced bioavailability. Drug and excipients studies were conducted using FTIR. Oral films of telmisartan were formulated using HPMC K4M as a film forming agent and propyl...

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  • NOVEL POLYMORPHIC FORM OF IMATINIB DRUG
    Salma A Bagwan*, N S Naikwade, K A Wadkar, S G Lokapure, Manure Md Javeed    Download Full Text

    Polymorphism is the ability of a solid material to exist in more than one form or crystal structure. The complete morphology of a material is described by polymorphism and other variables such as crystal habit, amorphous fraction or crystallographic defects. Polymorphism was done to increase the solubility and stability of drug. A number of methods have been employed for characterizing polymorphs ...

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  • SOLUBILITY ENHANCEMENT OF ANTI TB DRUG RIFAMPICIN BY SOLID DISPERSION TECHNIQUE
    Sakshi Ranawat, Kalpana Patidar*, Manish Soni    Download Full Text

    The present research work is an attempt to increase the solubility dissolution rate of rifampicin by solid dispersion as the poor solubility of drug substances in water and their low dissolution rate in aqueous G.I.T. fluid often leads to insufficient bioavailability, this low bioavailability leads to less therapeutic effect of particular drug. Rifampicin belongs to BCS class II, which is slightly...

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  • FORMULATION AND EVALUATION OF BUCCAL FILMS OF ONDANSETRON HYDROCHLORIDE
    Neha Sorayan*, Urmi Chaurasia    Download Full Text

    The present study involves the formulation and evaluation of buccal films of ondansetron HCl using HPMC K15M, eudragit RL-100 and chitosan in various proportions and combination. The films were fabricated by solvent casting method using. Ondansetron hydrochloride, an antiemetic drug has oral bioavailability of 60% due to hepatic first metabolism and a short half-life of 5 hrs. Buccal route is an e...

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  • MOST RECENT TECHNOLOGIES AND PRINCIPLES INVOLVED IN INDUSTRIALIZED MOUTH DISSOLVING TABLETS
    Suchi Thakur*, Pankaj Pawar, Misha Masood, Firdos Khan, Meghna A Singh    Download Full Text

    In recent decades, a variety of pharmaceutical research has been conducted to develop new dosage forms. The desire of improved palatability in orally administered products has prompted the development of numerous formulations with improved performance and acceptability. Mouth dissolving tablets (MDTs) have received ever-increasing demand during the last few decades and the field has become a rapid...

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  • ISOLATION AND EVALUATION OF HUSK FROM FENUGREEK SEED AS A GRANULATING AGENT IN THE FORMULATION OF TABLETS
    Priyanka P Bankar*, Subir K Banerjee    Download Full Text

    In present study a relatively simple method for the separation of husk from the seed of Trigonella-foenum graecum (Fenugreek) was developed. The entire seed were subjected to size reduction followed by successive extractions with chlorinated hydrocarbons to separate the husk from the ‘core and oily portion’ to yield about 40% w/w of the husk .The dried husk was further powdered to 180-250µ....

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