Inventi Rapid - NDDS
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: NDDS’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under novel drug delivery systems. It welcomes articles pertaining to nano drug delivery systems; gastroretensive system, colonic drug delivery, bioadhesive and mucoadhesive systems; nasopulmonary drug delivery; ocular delivery; transdermal delivery, implants and inserts; protein and peptide delivery; manufacturing, quality control and regulatory aspects of NDDS, etc.
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FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF TELMISARTAN
Research concept was to emphasize mainly on the merits of MDT as it counteracts the demerits of other conventional dosage form, i.e. dysphagia. MDT is a dosage form which disintegrates instantly when placed on tongue, releases the medicament that dissolves/disperses in the saliva. Telmisartan which is a BCS class II anti-hypertensive drug is framed into its sodium salt form, increasing its solubil...
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DEVELOPMENT AND EVALUATION OF THIOCOLCHICOSIDE LOADED MICROSPHERES
Thiocolchicoside is a semi synthetic drug derived from colchicoside used as a muscle relaxant as well as an anti-inflammatory agent. It has high aqueous solubility and low bioavailability. Hence, the aim of this study was to prolong the release of thiocolchicoside by developing polymeric microspheres. Microspheres were produced by ionotropic gelation technique to prolong the release of thiocolchic...
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SYSTEMIC ENHANCEMENT OF NEBIVOLOL BY USING NANOSUSPENSION IN-SITU NASAL SPRAY
Nebivolol mucoadhesive nasal spray increasing the drug residence time in the nasal cavity and nanosuspension enhance the systemic availability. Nanosuspension was prepared by top down media milling technique by using ZrO2. Nanosuspension was optimized by using various concentrations of stabilizers and various concentrations of ZrO2 beads. Optimized nanosuspension were evaluated for particle size, ...
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FORMULATION AND EVALUATION OF BUCCAL MUCOADHESIVE PATCHES FOR THE TREATMENT OF HYPERTENSION
Nimodipine is dihydropyridine calcium channel blocker, generally used for the treatment of high blood pressure. It has shown the good results in preventing major issues of subarachnoid hemorrhage (a form of cerebral hemorrhage) termed vasospasm; this is currently the main use of nimodipine. In the present study buccal drug delivery of nimodipine was developed. Matrix type of buccal patches was dev...
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WHY? VAGINAL DRUG DELIVERY SYSTEM FOR PROGESTERONE AND ESTROGEN
Vaginal route is one of the underutilized route of administration which is known since ancient time, but nowadays it is gaining importance because of advanced formulation technologies which include effervescent technology, Bio-adhesive technology and vaginal rings. Vaginal route remains a promising route when the drug undergoes gastric disintegration (Progesterone) and hepatic first pass (Estrogen...
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RELEASE MODULATING HYDROPHILIC MATRIX SYSTEMS OF NIFEDIPINE EXTENDED RELEASE TABLETS: OPTIMIZATION OF FORMULATION USING 32 FULL FACTORIAL DESIGN
The objective of the present research work was to systemically device a model of nifedipine extended release tablet and optimization of drug release according to the U.S.P. In this study, the nifedipine extended release tablet were formulated using polymer HPMC K4M and HPMC K100M by wet granulation method and HPMC K4M was also added extra granularly. These formulations were evaluated for the param...
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