Inventi Rapid - NDDS
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: NDDS’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under novel drug delivery systems. It welcomes articles pertaining to nano drug delivery systems; gastroretensive system, colonic drug delivery, bioadhesive and mucoadhesive systems; nasopulmonary drug delivery; ocular delivery; transdermal delivery, implants and inserts; protein and peptide delivery; manufacturing, quality control and regulatory aspects of NDDS, etc.
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FORMULATION AND EVALUATION OF TOPICAL GEL USING OCIMUM BASILICUM EXTRACT CONTAINING KETOCONAZOLE FOR SKIN DISEASES
Topical delivery is an attractive route for the local and systemic treatment. The delivery of the drugs onto the skin is recognized as an effective means of therapy for local dermatologic diseases. Topical gels are becoming more popular due to ease of application and better precutaneous absorption. Topical gel drug administration is a localized drug delivery system anywhere in the body through oph...
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CHITOSAN: AN INTELLIGENT POLYMER FOR NOVEL DRUG DELIVERY SYSTEM
Chitosan has been worldwide exploited as a system to fulfill requirements in terms of patient compliance and marvelous therapeutic efficacy. These systems involve precise control over release profile of drug at a specific site in targeted delivery. This review insight on chitosan’s physicochemical and biological characteristics and reflect its role and application pharmaceutical approaches. Chit...
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DESIGN AND CHARACTERIZATION OF ACYCLOVIR NANOCRYSTALS FOR ENHANCEMENT OF SOLUBILITY AND BIOAVAILABILITY
The objective of this research work was to enhance solubility and dissolution profile of acyclovir. Nanocrystals were prepared by an anti-solvent precipitation process supplemented by sonication using different stabilizers. The formed nanocrystals were of 376-1085 nm in size. Formulations NC7 and NC8 showed marked improvement in dissolution compared to pure drug, thus greater bioavailability. Thes...
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DEVELOPMENT AND CHARACTERIZATION OF COLON PH TRIGGERED MULTIPARTICULATE DRUG DELIVERY SYSTEM FOR ULCERATIVE COLITIS
The purpose of the present study was to develop and characterize mesalamine microsphere to target colon for ulcerative colitis. Mesalamine is a drug with low solubility so in order to increase its solubility the solid dispersions of mesalamine were prepared by using kneading method with three different carriers, poly vinyl pyyrolidone (PVP K-30), poly ethylene glycol (PEG 4000) and β-cyclodextrin...
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DESIGN, DEVELOPMENT AND EVALUATION OF ORLISTAT LIPOSOMAL DRUG DELIVERY SYSTEMS
In this study, orlistat liposomes were developed and characterized for the physical as well as chemical parameters by ethanol injection method. Formula optimization studies were utilized to investigate the impact of different molar ratios of orlistat drug, soya phosphatidylcholine and cholesterol on physical appearance, pH, density, % drug entrapment efficiency, particle size, polydispersity index...
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DESIGN AND EVALUATION OF COLON SPECIFIC MICROSPONZES OF MESALAMINE
Mesalamine is used for ulcerative colitis, colon cancer. Microsponges are porous, polymeric microspheres that are designed to deliver a pharmaceutical active ingredient efficiently at the minimum dose and also to, modify drug release. The present work was aimed at designing microsponge based colon specific drug delivery system containing mesalamine, Eudragit RS-100, Eudragit RL-100 ba...
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