Inventi Rapid - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ATENOLOL AND LERCANIDIPINE IN BULK FORM BY UV-SPECTROPHOTOMETER
The UV-spectrophotometric method by simultaneous estimation has been developed for atenolol (ATN) and lercanidipine (LCD) showed absorbance maxima at 224.0 nm and 238.0 nm, respectively. Both of these drugs, obeyed linearity in the concentration range 4 - 28 µg/ml at their respective wavelengths. The proposed method was applied for bulk drug. The accuracy of the method was assessed by recovery ...
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NOVEL RP-HPLC ASSAY FOR THE ESTIMATION OF TRAMADOL HCL IN TABLET FORMULATION: METHOD DEVELOPMENT AND VALIDATION
A novel RP-HPLC method has been developed for the estimation of tramadol hydrochloride (TH) in the tablet dosage form using Phenomenox C18 column of dimensions 250 x 4.6 mm i.d., particle size 5 μm utilizing the system of buffer: acetonitrile (55:45 ratio) as the mobile phase at a flow rate of 1 ml/min, employing 271 nm detector, where the drug was eluted at 6.21 minutes. The newly developed meth...
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DETERMINATION OF SORBIC ACID AND BENZOIC ACID USING REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC) IN DIFFERENT FOOD COMMODITIES
The aim of this work was the determination and the analysis of benzoic acid and sorbic acid content in carbonated and non-carbonated beverages, in addition to cake, biscuit, yoghurt, sauce, ketchup, mayonnaise, croissant and jam products. The analyses of these preservatives in 60 different food products were performed. In this purpose, the conditions of analyzed compounds extraction from the food ...
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IONIZATION SOURCES USED IN MASS SPECTROSCOPY: A REVIEW
Mass spectrometry is a powerful technique for identification of unknowns and study of molecular structure of various compounds. Mass spectrometry is an analytical technique for “weighing” molecules. Mass spectrometry is based upon the principle of the motion of a charged particle that is called an ion, in an electric or magnetic field. The mass to charge ratio of the ion affects particles moti...
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STABILITY INDICATING RP- HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF GATIFLOXACIN AND DEXAMETHASONE SODIUM PHOSPHATE IN OPHTHALMIC FORMULATION
A simple, accurate and precise stability indicating RP-HPLC method was developed for the simultaneous estimation of dexamethasone sodium phosphate (DSP) and gatifloxacin (GA) in ophthalmic formulation. Method was achieved in various degradation condition like acidic, basic, oxidative, thermal and photolytic. Maximum degradation was found to be in acidic condition for DSP 29% and for GA in thermal ...
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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF HYDROCHLOROTHIAZIDE AND SPIRANOLACTONE IN ITS COMBINED DOSAGE FORM
A new simple, sensitive and reproducible RP-HPLC method for the simultaneous estimation of hydrochlorothiazide and spiranolactone in pharmaceutical formulations was developed and validated. The separation was carried out on Phenomenex kinetex C18, 5μm (250×4.6 mm) column with acetonitrile: sodium dihydrogen and disodium hydrogen orthophasphate pH 6.4, 50:50% v/v as the mobile phase at the flow r...
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