Inventi Rapid - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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A SIMPLE, PRECISE RP-HPLC METHOD FOR THE DEVELOPMENT AND VALIDATION OF FOOD SUPPLEMENTS, L-CARNITINE AND L-TARTRATE IN BULK AND TABLET FORMS
A simple, efficient, precise and isocratic reverse phase-high performance liquid chromatographic method was developed and validated as per ICH guidelines for the determination of L-Carnitine and L-Tartrate in bulk and pharmaceutical dosage form. The chromatographic separation was achieved by using Prontosil, C18, 5µ, (4.6 x 250) column at ambient temperature (300c). Mobile phase comprises of Orth...
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A STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF EMPAGLIFLOZIN AND LINAGLIPTIN IN COMBINED TABLET DOSAGE FORMS
A rapid and sensitive stability indicating RP-HPLC method was developed for simultaneous estimation of empagliflozin and linagliptin in combined tablet formulations. Chromatography was carried out on a Thermo Scientificâ„¢ Hypersil ODS C18 HPLC Column (150 x 4.6 mm; 5 m particle size) by eluting with a mobile phase consisting of a 45:55 v/v mixture of 0.1 % orthophosphoric acid in water and aceton...
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A STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF DAPAGLIFLOZIN AND SAXAGLIPTIN IN COMBINED TABLET DOSAGE FORMS
A rapid and sensitive stability indicating RP-HPLC method was developed for simultaneous estimation of dapagliflozin and saxagliptin in combined tablet formulations. Chromatography was carried out on a Kromasil® C18 HPLC Column (250 x 4.6 mm; 5m; 30°C) by eluting with a mobile phase consisting of a 50:50 v/v mixture of acetonitrile and 0.1 % orthophosphoric acid in water at a flow rate of 1.0 ml...
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REVIEW ON ANTI-CANCER AGENTS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC METHODS
The main aim of this review is to provide the overview on estimation of anticancer drugs by various high performance liquid chromatographic methods. In present scenario, the most common analytical method employed for estimation of drugs is reverse phase high pressure liquid chromatography (RP-HPLC) because of its high sensitivity and speed. Analytical method development and validation is an import...
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FORCED DEGRADATION STUDY OF TRAMADOL HCL BY UV SPECTROSCOPY
The objective of present study was to develop and validate forced degradation studies to generate reliable and accurate data regardless of whether it is for acceptance, release, stability or pharmacokinetic study. Tramadol hydrochloride is a centrally acting synthetic opioid analgesic binding to specific opioid receptors. Tramadol HCl was freely soluble in methanol and practically soluble in water...
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STABILITY INDICATING UV SPECTROPHOTOMETRIC METHOD DEVELOPMENT OF ETORICOXIB
Etoricoxib is a NSAID which inhibits synthesis of prostaglandins by inhibiting the activity of the enzyme cyclo-oxygenase-2(COX-2) which is administered orally as an analgesic and anti-inflammatory drug that is used for the treatment of osteoarthritis, rheumatoid arthritis and gouty arthritis. The objective of present study was to develop stability indicating method to generate reliable and accura...
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