Inventi Rapid - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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RAPID PHARMACEUTICAL ESTIMATION OF NOVEL SGC STIMULATOR RIOCIGUAT USING ABSORBANCE AND DERIVATIVE UV-SPECTROSCOPY
Simple and rapid uv-spectrophotometric methods were investigated for pharmaceutical estimation of riociguat (RCG). RCG is a novel soluble guanylate cyclase (sGC) stimulator. We report here; zero order absorbance (Method I) and first order derivative UV-spectroscopy (Method II) for RCG. The analysis involved the use of methanol as solvent for determination of RCG using for both methods. The drug wa...
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QUANTITATIVE DETERMINATION OF PROCHLORPERAZINE EDISYLATE IN BULK AND PHARMACEUTICAL DOSAGE FORM BY ZERO ORDER UV-SPECTROPHOTOMETRY
Two simple UV-Spectrophotometric methods have been developed for the estimation of Prochlorperazine Edisylate (PCE) in tablets and parenteral dosage form by using Zero-order UV-Spectrophotometry absorbance method (Method I) and Zero order UV-Spectrophotometry method using the area under curve technique (Method II). Water was used as a solvent. The L-max of PCE in water was found to be 255 nm. In ...
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CHROMATOGRAPHIC EVALUATION OF ETHANOLIC STEM EXTRACT OF VENTILAGO MADERASPATANA GRAETN
Chromatographic studies were carried out on ethanolic stem extract of Ventilago maderspatana Gaertn belonging to the family Rhamnaceae. It is an important and well known plant in the Indian system of medicine. Stem samples of V. maderspatana was subjected to maceration by using distilled water and ethanol. Ethanolic extract was prepared from the stem, of Ventilago maderspatana. Preliminary phytoch...
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QUALITY BY DESIGN: AN APPROACH FOR FORMULATION DEVELOPMENT
Quality by design is the modern approach for quality of pharmaceutical. It serves as a bridge between industry and drug regulatory authorities to move towards a scientific, risk based holistic and protective approach for development of pharmaceutical product. The purpose of this project is to discuss the pharmaceutical quality by design and describe how it can be used to ensure pharmaceutical qual...
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STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF OFLOXACIN AND RACECADOTRIL IN TABLET DOSAGE FORM
A simple stability indicating HPLC method was developed and validated for the estimation of ofloxacin and racecadotril in tablet dosage form. Optimized method was developed using discovery C8 column (250×4.6 mm, 5µ) at 295 nm using a mobile phase composition of acetonitrile and orthophosphate buffer of pH 4.8(55:45 v/v) at a flow rate of 1 ml/min. Injection volume was selected to be 10 µl and r...
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DEVELOPMENT OF NEW SPECTROMETRIC METHOD FOR ESTIMATION OF ENTECAVIR MONOHYDRATE IN FORMULATION USING MBTH AS CHROMOGENIC REAGENT
A visible spectrophotometric method have been developed for the determination of entecavir monohydrate in pure and dosage forms using MBTH as chromogenic reagent. Present study is based on oxidation followed by coupling by 3-methyl-2-benzothiazolinone hydrazone with drug in the presence of cerric ammonium nitrate to form blue-green colored chromogen exhibiting absorption maximum a...
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