Inventi Rapid - Pharm Analysis & Quality Assurance
-
Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
-
CHROMATOGRAPHIC EVALUATION OF ETHANOLIC STEM EXTRACT OF VENTILAGO MADERASPATANA GRAETN
Chromatographic studies were carried out on ethanolic stem extract of Ventilago maderspatana Gaertn belonging to the family Rhamnaceae. It is an important and well known plant in the Indian system of medicine. Stem samples of V. maderspatana was subjected to maceration by using distilled water and ethanol. Ethanolic extract was prepared from the stem, of Ventilago maderspatana. Preliminary phytoch...
Read More -
QUALITY BY DESIGN: AN APPROACH FOR FORMULATION DEVELOPMENT
Quality by design is the modern approach for quality of pharmaceutical. It serves as a bridge between industry and drug regulatory authorities to move towards a scientific, risk based holistic and protective approach for development of pharmaceutical product. The purpose of this project is to discuss the pharmaceutical quality by design and describe how it can be used to ensure pharmaceutical qual...
Read More -
STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF OFLOXACIN AND RACECADOTRIL IN TABLET DOSAGE FORM
A simple stability indicating HPLC method was developed and validated for the estimation of ofloxacin and racecadotril in tablet dosage form. Optimized method was developed using discovery C8 column (250×4.6 mm, 5µ) at 295 nm using a mobile phase composition of acetonitrile and orthophosphate buffer of pH 4.8(55:45 v/v) at a flow rate of 1 ml/min. Injection volume was selected to be 10 µl and r...
Read More -
DEVELOPMENT OF NEW SPECTROMETRIC METHOD FOR ESTIMATION OF ENTECAVIR MONOHYDRATE IN FORMULATION USING MBTH AS CHROMOGENIC REAGENT
A visible spectrophotometric method have been developed for the determination of entecavir monohydrate in pure and dosage forms using MBTH as chromogenic reagent. Present study is based on oxidation followed by coupling by 3-methyl-2-benzothiazolinone hydrazone with drug in the presence of cerric ammonium nitrate to form blue-green colored chromogen exhibiting absorption maximum a...
Read More -
DEVELOPMENT AND VALIDATION OF COLORIMETRIC METHOD FOR QUANTITATIVE ESTIMATION OF GEMCITABINE HYDROCHLORIDE IN BULK AND DOSAGE FORM
Gemcitabine hydrochloride is used as an anti-cancer drug. The aim of this study was to develop colorimetric method for the estimation of gemcitabine in bulk and lyophilized powder for injection. In colorimetric method the absorption maximum was found to be 556 nm and beer’s law obeyed in the concentration range of 10-30 µg/ml. The LOD and LOQ were found to be 0.27 and 0.84 µg/ml respectively w...
Read More -
DEVELOPMENT AND VALIDATION OF ZERO ORDER UV-SPECTROPHOTOMETRIC METHOD BY AREA UNDER CURVE TECHNIQUE AND HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY FOR THE ESTIMATION OF REMOGLIFLOZIN ETABONATE IN BULK AND IN-HOUSE TABLETS
The proposed study described the development of two simple, accurate, cost effective and rapid zero order uv-spectrophotometric-AUC method and high-performance thin layer chromatographic (HPTLC) method for the estimation of remogliflozin etabonate in bulk and in-house Tablets. Remogliflozin etabonate showed maximum absorbance at 225 nm in methanol. For UV-AUC method wavelengths 216.80 nm and 232 n...
Read More