Inventi Rapid - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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AREA UNDER CURVE UV SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF GLICLAZIDE IN BULK AND FORMULATION
The article describes a simple, sensitive, rapid, accurate and precise spectrophotometric method for the determination of gliclazide in bulk and pharmaceutical dosage forms by utilizing area under curve (AUC) method. The new method is area under curve method for the analysis of gliclazide using methanol as solvent for the drug. Gliclazide has absorbance maxima at 228.20 nm at area under curve wave...
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ESTIMATION OF DISULFIRAM IN BULK AND FORMULATION BY UV-SPECTROPHOTOMETRIC AREA UNDER CURVE METHOD
The current work was carried out for estimation of disulfiram in bulk and pharmaceutical dosage form by utilizing area under curve (AUC) method. For this purpose the wavelength range 204-230 nm was selected. Methanol was used as a solvent throughout the work. Linearity was observed in concentration range 5-25 µg/ml (r2 = 0.99) for the method. Recovery studies for area under curve were found to be...
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SIMULTANEOUS ESTIMATION OF RIBOCICLIB AND PALBOCICLIB IN BULK SAMPLES BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
This work concerns with the development and validation of a simple, specific and cost effective RP-HPLC method for simultaneous estimation of ribociclib and palbociclib in bulk samples. Chromatography was carried on Kromasil C18 column with mobile phase comprising of 20 mM phosphate buffer (pH-5): methanol: acetonitrile (40:30:30, v/v/v). The flow rate was adjusted to 1 ml/min with PDA detection a...
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ANALYTICAL METHOD DEVELOPMENT AND INVESTIGATION OF CAFFEINE CONTENT FROM COFFEA ARABICA AND ANTI-OBESITY FORMULATION AS PER ICH Q2 (R1) PROTOCOL OF VALIDATION
Precise and sophisticated HPTLC and HPLC methods were developed for determination of caffeine from coffee bean extract. HPTLC analysis was performed on silica gel 60 F254 plate using ethyl acetate: methanol: water in the proportion of 10: 1.4: 1 (v/v/v) as mobile phase. A clear band of caffeine was observed at Rf value 0.55 (+0.1). Caffeine shows linearity within the concentration range of 200-600...
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AN EXPERIMENTAL APPROACH TOWARDS STABILITY STUDY OF PHARMACEUTICALS
The stability study is one of the very important parameter for pharmaceutical products. Stability studies are performed at various stages of drug development process to assure efficacy of drug. Stability is an essential factor of quality, safety and efficacy of a drug product. The objective of stability study is to determine the estimation of shelf life, the time period of storage at a specified c...
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USE OF CHEMOMETRICS IN ESTIMATION OF PHARMACEUTICAL COMPONENTS
For estimation of certain properties of molecule, useful information can be obtained from physical and other chemical phenomenon and transformed by mathematical and statistical method which is known as chemometrics. Many calibration problems related to analysis of spectral data can be solved by using chemometrics method. This review article mainly involves different chemometrics method and how we ...
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