Inventi Rapid - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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SIMULTANEOUS ESTIMATION OF MOXIFLOXACIN AND CEFEXIME TRIHYDRATE IN BULK AND TABLET FORMULATION BY HPLC AND HPTLC ANALYSIS
Chromatography is the science which deals with the separation of molecules based on differences in their structure and composition. In present study the analytical methods were developed and validated for anti bacterial drug in bulk and multiple component formulation. In the first part HPLC method was developed and validated for both moxifloxacin and cefixime in bulk and tablet formulation (Alexim...
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FORCED DEGRADATION STUDY: AN ESSENTIAL APPROACH TO DEVELOP STABILITY INDICATING METHOD
Forced degradation is the study of the chemical stability of a new drug product and drug substance at the condition of more severe than accelerated condition. The forced degradation study illustrates the chemical stability of the drug molecules which further facilitates the development of stable formulation with suitable storage conditions. Regulatory guideline USFDA, ICH, EMA, ANVISA demonstrate ...
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QUANTIFICATION OF ANTIBIOTIC RESIDUES IN RAW AND LAYERS HEN EGGS BY RP-HPLC
The objective of this study was to quantify the antibiotics (oxytetracycline and enrofloxacin) residue levels in raw and layers by RP-HPLC. This study was carried out on one hundred randomly collected raw and layers hen egg samples (20 of each) to evaluate the antibiotic (oxytetracycline and enrofloxacin) residues level qualitatively by high performance liquid chromatography (HPLC). The separation...
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REVIEW ON ANALYTICAL METHODS FOR DETERMINATION OF HYDROXYLAMINE GENOTOXIC IMPURITY IN PHARMACEUTICAL PRODUCTS AND WASTE STREAMS GENERATED BY A PHARMACEUTICAL REACTION PROCESS
Hydroxylamine (HYX) is a vital class of reducing chemical compound, which is generally used as an industrial raw material in pharmaceutical reaction processes. The key concern is drug protection because if repeated exposure to GIT compounds that can damage DNA by alkylation leads to a mutation on genetic codes such impurities can react with mutation-causing DNA bases and have toxic effects such as...
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STANDARDIZATION OF BIBHITAKADI GHRITA
Bibhitakadi Ghrita (BG) is mentioned in Netrarogadhikara by Yogratnakara. Along with its modern management this drug might be useful in treating Presbyopia. Bibhitakadi Ghrita was processed as per the process of Snehapaka procedure described in classics. It contained Bibhitaki (Terminalia bellirica), Haritaki (Terminalia chebula), Amalaki (Embilica officinalis), Nimba (Azadirachta indica), Patola ...
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DEVELOPMENT AND VALIDATION OF THE ANALYTICAL METHOD FOR DETERMINATION OF ANTI-TUBERCULOSIS DRUGS BY USING RP-HPLC METHOD
A simple, accurate and validated liquid chromatographic method was developed for the estimation of rifampicin (RIF) and isoniazid (INH) in bulk and combined dosage forms. Drugs were injected in a chromatographic system on a reverse-phase C8 column using a mobile phase composition of Acetonitrile: Ammonium acetate buffer (50:50), isocratically and monitored at the analogous maximum of each compound...
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