Inventi Rapid - Pharm Analysis & Quality Assurance
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharm Analysis & Quality Assurance’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under pharmaceutical analysis and quality assurance. It welcomes articles pertaining to qualitative and quantitative analysis of drugs, excipients, and impurities etc. to meet the regulatory requirements; analysis of modern and traditional medicines; quality control methods for biological drugs; quantitative and qualitative analysis in the drug screening processes; tracer analysis in molecular pharmacology; clinical and biological analysis, etc.
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PHARMACOLOGICAL EVALUATION OF BETA SECRETASE INHIBITORS
Alzheimer’s disease (AD) progresses due to beta amyloid aggregation and decreased acetylcholine level. Amyloid-Beta peptide (ABeta) formed by the continuous proteolytic processing of Beta-amyloid precursor protein (Beta APP) by Beta-secretase (BACE1) and Gamma-secretase (BACE2), plays a vital role in the pathogenesis of alzheimer’s disease (AD). Evaluated dipeptides and octapeptides exhibit in...
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DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF CLOTRIMAZOLE, CLINDAMYCIN PHOSPHATE AND TINIDAZOLE CAPSULE
Stability indicating RP-HPLC method for simultaneous estimation of clotrimazole, clindamycin phosphate and tinidazole in their combined dosage form has been developed. The separation was achieved by Shimadzu LC-10AT Hypersil BDS C18 column and buffer (pH 4.5): acetonitrile (60:40) as mobile phase, at a flow rate of 1 ml/min. Detection was carried out at 230 nm. Retention time of clotrimazole, tini...
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CHROMATOGRAPHIC EVALUATION OF ETHANOLIC LEAF EXTRACT OF VENTILAGO MADERASPATANA GRAETN
Chromatographic studies were carried out on ethanolic leaves extract of Ventilago maderspatana Gaertn belonging to the family Rhamnaceae. It is an important and well known plant in the Indian system of medicine. Leaf samples of V. maderspatana were subjected to maceration by using distilled water and ethanol. Ethanolic extract was prepared from the leaf, of Ventilago maderspatana. Preliminary phyt...
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CHROMATOGRAPHIC EVALUATION OF AQUEOUS STEM EXTRACT OF VENTILAGO MADERASPATANA GRAETN
Chromatographic studies were carried out on aqueous stem extract of Ventilago maderspatana Gaertn belonging to the family Rhamnaceae. It is an important and well known plant in the Indian system of medicine. Stem samples of V. maderspatana was subjected to maceration by using distilled water and ethanol. Aqueous extract was prepared from the stem, of Ventilago maderspatana. Preliminary phytochemic...
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AREA UNDER CURVE UV SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF GLICLAZIDE IN BULK AND FORMULATION
The article describes a simple, sensitive, rapid, accurate and precise spectrophotometric method for the determination of gliclazide in bulk and pharmaceutical dosage forms by utilizing area under curve (AUC) method. The new method is area under curve method for the analysis of gliclazide using methanol as solvent for the drug. Gliclazide has absorbance maxima at 228.20 nm at area under curve wave...
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ESTIMATION OF DISULFIRAM IN BULK AND FORMULATION BY UV-SPECTROPHOTOMETRIC AREA UNDER CURVE METHOD
The current work was carried out for estimation of disulfiram in bulk and pharmaceutical dosage form by utilizing area under curve (AUC) method. For this purpose the wavelength range 204-230 nm was selected. Methanol was used as a solvent throughout the work. Linearity was observed in concentration range 5-25 µg/ml (r2 = 0.99) for the method. Recovery studies for area under curve were found to be...
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