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Inventi Rapid - Med Chem

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: Med Chem’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under medicinal and pharmaceutical chemistry. It welcomes articles pertaining to design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or ligands employed as pharmaceutical tools; molecular modifications of reported series leading to improved understanding of SAR; structural biological studies of relevant ligands and targets; computational chemistry methods; effect of molecular structure on biopharmaceutics, etc.

  • SYNTHESIS AND CHARACTERIZATION OF SOME COUMARIN SCHIFF BASES AS POSSIBLE ANTITUBERCULAR AND ANTIBACTERIAL AGENTS
    Bharatesh S Kittur*, Shreenivas R Deshpande, Prashant S Munnolli, Prasad V Malagi, Sadanand N Masuti, Bhumika B Kittur    Download Full Text

    A series of coumarin Schiff bases, (E)-N’arylidine-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)-acetohydrazides (IVa-m) were synthesized by the reaction of intermediate, acetohydrazide of coumarin(III) with different aryl/hetero aromatic aldehydes in chloroform:methanol (1:1) mixture, in presence of glacial acetic acid and characterized by IR, NMR and Mass spectral data. The title compounds were evalu...

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  • SYNTHESIS OF IMIDAZOLE AND ITS DERIVATIVES: A REVIEW
    Umang A Gosalia*    Download Full Text

    Imidazole is a 5 membered aromatic diazole, having diverse pharmacological activity within its nucleus. A variety of synthetic methods are available in the literature but fact is that, there still remains a huge potential for the development of innovative, versatile, economical, simple, non-hazardous and green synthetic approaches to synthesize imidazole and its derivatives....

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  • SYNTHESIS OF NEW QUINOLONE COMPOUNDS AND ITS EVALUATION
    Verma Vikrant*    Download Full Text

    Quinolones has become a nucleus for novel research because its medicinal properties are well established. Quinoline ring has vast majority of pharmacological activities like antitumor, FMS Kinase Inhibitor, antibiotic, anti HIV and antibiotic. In this research novel quinolones are synthesized by innovative method by substitution at two different positions in the ring. Mainly the antibacterial acti...

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  • PYRIMIDINE DERIVATIVES: SYNTHESIS AND BIOACTIVITIES
    Kadam S S*, Pawar P Y    Download Full Text

    Pyrimidine and their derivatives are endlessly pulling attention of the medicinal chemists in view of long and notable history extending from the day of their discovery as, important constituents of nucleic acid. Pyrimidine and its derivatives demonstrate a diverse array of biological and pharmacological activities including anticonvulsant, antibacterial, antifungal, antiviral and anticancer prope...

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  • A BRIEF REVIEW ON SOME NOVEL PROMISING MOLECULES AS ANTITUBERCULAR AGENTS
    Shirkhedkar Atul A, Ghodke Mangesh S*, Surana Sanjay J    Download Full Text

    As one third of the world’s population is infected with M. tuberculosis along with this new and relapse cases of tuberculosis are reported every year. The emergence of new cases, increased incidence of multi-drug resistant strains of M. tuberculosis and the side effects of existing first- and second-line antituberculosis drugs have led to hope of discovering new antitubercular drug molecule...

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  • KINETICS APPROACH FOR OXIDATION OF BENZALDEHYDE AND P-NITRO BENZALDEHYDE BY ISOQUINOLINIUM BROMOCHROMATE IN AQUEOUS ACETIC ACID MEDIUM
    Diwakar Prasad Sharma*, Dharmendra Dwivedi    Download Full Text

    In chemical kinetics, the rate and mechanism of a chemical reaction is to determine the overall stoichiometry of the reaction and to identify any side‐reaction. This study involves the determination of the effect of changes in the concentrations of reactant and product species. One reason for studying the rates of the reaction is to predict how quickly a reaction mixture approaches equilibri...

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