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Inventi Rapid - Animal Models & Cell Assays

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: Animal Models & Cell Assays’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. It focuses on multidimensional aspects of animal models and cell assays particularly leading to bio-profiling and drug development. The journal accepts articles based on in-vivo studies, as well as in-vitro.

  • SYSTEMATIC REVIEW OF PLURIPOTENT STEM CELLS AS A POTENTIAL THERAPY FOR VARIOUS AUTOIMMUNE DISEASES
    Priyanka Nigade*, Harshad Choudhari    Download Full Text

    Pluripotency is the capability of cell to develop into all of the cells of an embryo. In human body there are certain types of cells which are having this property. For example hematopoietic cells, lymphocytes stem cells etc. They can differentiate into large variety of cells with different functions but they all work together as a part of immune system. They are able to self-renew means they can ...

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  • IN-VITRO GLUCOSE UPTAKE ASSAY OF HYDRO METHANOLIC LEAVES EXTRACT OF SYZYGIUM JAMBOS (L) ALSTON IN RAT SKELETAL MUSCLE (L6) CELL LINES
    Yarasu Nagamuni Reddy, P Smana Reddy, M Sadhvi, R Pavan Kumar, R N B S Nareshchandra, V Vinil Kumar    Download Full Text

    The purpose of the present study to investigate the Invitro glucose uptake assay of hydromethanolic leaves extract of Syzygium jambos (L) Alston (SJM) on L6 Cell lines. Syzygium jambos (L) Alston Commonly known as rose apple belongs to family Myrtaceae , It is one of the most important medicinal plant in India, Brazil. In Brazil decoction of leaves used for diabetes. Hydromethanolic leaves extract...

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  • SCREENING OF ANTITHROMBOTIC ACTIVITY OF ANTIPLATELET DRUGS TREATED SWISS MICE
    Abhishek Sharma, Deepak Sharma, Jay Singh Vaghela    Download Full Text

    To estimate antithrombotic effect of antiplatelet drugs, in collagen epinephrine treated swiss mice. Lung damage (pulmonary thromboembolism) in swiss mice treated with collagen (1.5 mg/kg) and epinephrine (0.5 mg/kg) by tail vein was studied by assessing parameters such as percentage protection. The effect of antiplatelet drugs (30µM oral) on above parameters was investigated .This biochemical ob...

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  • ANIMAL MODELS OF INFLAMMATORY BOWEL DISEASE
    Ashmita Bhalodiya*, Vidhi Dhagia, Mehul Chorawala, Gaurang Shah    Download Full Text

    Crohn’s disease and ulcerative colitis are chronic inflammatory disorder of the intestine referred as inflammatory bowel disease. Interaction between genetic, environmental and immunological factors contributes disease investigation and profession. Investigation of receptor mediated and intracellular signalling pathway related to immune interaction with gut microbiota and genetic study in humans...

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  • ANTITHYROID AGENTS: A REVIEW ON PRECLINICAL EVALUATION WITH AN OVERVIEW OF PHARMACOTHERAPY
    A C Joshi*, A V Jaydeokar, R D Khose, S M Chaudhari, P P Bagul, D D Bandawane, P D Chaudhari    Download Full Text

    ABSTRACT Thyroid gland is the major endocrine gland of the body. The pituitary thyroid system is responsible for regulating daily function of many biological systems by producing thyroid hormones, the principal ones being triiodothyronine (T3) and thyroxine. Thyroid hormones (T3, T4) are essential for normal development and growth. The most common problems of the thyroid gland consist of an overa...

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  • SCREENING METHODS OF ANTIULCER AGENTS
    P P Gadhaave*, D D Bandawane, P D Chaudhari    Download Full Text

    Gastric ulcer is corrosive action of acid on the mucosa of the upper gastrointestinal tract. Ulcers can develop in the esophagus, stomach or duodenum. Peptic ulcer (PU) disease represents a worldwide health problem due to morbidity, mortality and economic loss. H pylori infection, tobacco smoking, and use of minor tranquillizers were the main risk factors for PU in this population. Researchers dev...

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