Inventi Rapid - Pharmaceutical Process Development
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Journal Scope:
Quarterly published in print and online ‘Inventi Rapid/Impact: Pharmaceutical Process Development’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. It focuses on multidimensional aspects of pharmaceutical process development, particularly – ingredients and equipment selection, scale-up and pilot plant studies, factoring environment, automaton and robotic procedures, in-process characterization, bioprocesses etc.
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FORMULATION, DEVELOPMENT AND EVALUATION OF GEL CONTAINING PSIDIUM GUAJAVA LEAVES EXTRACTS BY DESIGN EXPERT APPROACH
Psidium guajava Linn (Myrtaceae) has been used as traditional medicine. The aim of the present research work was to investigate the gel formulation containing hydroalcoholic and methanolic extract of Psidium guajava leaves. Quercetin was taken as marker and it shows good in-vitro drug release from the results it was concluded that psidium guajava leaves extract when formulated in gel show signific...
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DICLOFENAC SODIUM LOADED SUSTAINED RELEASE MATRIX TABLET POSSESSING HYDROPHOBIC POLYMERS: FORMULATION AND IN-VITRO CHARACTERIZATION BY USING MELT GRANULATION
Sustained release products are designed to release their medication in a controlled manner, at a predetermined rate, duration and location to achieve and maintain optimum therapeutic blood levels of drug. In case of simple matrix tablet, use of drug with high water solubility is accompanied by problems, i.e. relatively large amount of release-delaying agent is needed and the size of tablet as well...
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SOLID DISPERSIONS: SOLUBILITY ENHANCEMENT TECHNIQUE FOR CINNARIZINE POORLY WATER SOLUBLE DRUGS
Solid dispersions have been known to be one amongst the recent means of improving the dissolution rate by enhancement of solubility and hence the bioavailability of poorly water soluble drugs. Solid dispersion nothing to the “The dispersion of one or more active ingredients in an inert carrier or matrix, where the active ingredients could exist in finely crystalline, solubilized or amorphous sta...
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QUALITY BY DESIGN (QBD) PRINCIPLES AND APPLICATIONS IN PRODUCT DEVELOPMENT: AN OVERVIEW
The purpose of present article is to discuss the concept of pharmaceutical Quality by Design (QbD) and describe how it can be help to ensure pharmaceutical quality. Quality by Design is the modern approach for quality of pharmaceuticals. There is much confusion among pharmaceutical scientists in generic drug industry about the appropriate element and terminology of quality by design. Implementatio...
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A REVIEW: STABILITY STUDIES AN IMPORTANT FOR PHARMACEUTICAL’S
Stability means the time during which the drug product remain in its same property and characters. Stability study necessary during the decomposition of active drug, toxic product may be formed. In manufacturing, good formulation will taken long time for decomposition. Drug degradation has studied individually but it time consuming. In accelerated stability testing to predict the shelf life of a p...
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SIX SIGMA AND LEAN SIX SIGMA METHODOLOGY: A REVIEW
Six sigma is a statistical concept which helps us to define the problems systematically, provides tools to measure and analyze the influential factors, identifies the improvements that can be implemented easily and ensure that the changes which have been made, are kept alive through a control process and maintains the gains over the time. It is a known fact that in a process with six sigma capabil...
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