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Inventi Rapid - Molecular Pharmacology

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: Molecular Pharmacology’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas in the growing field of molecular pharmacology. It aims to cover the developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, and proteomics.

  • RESTORATIVE POTENTIAL OF CURCUMIN IN PARKINSON’S DISEASE THERAPEUTICS
    Rohit Ramesh Doke*, Kedar Vijaykumar Lakhdive    Download Full Text

    Parkinson’s disease (PD) is an age-associated neurodegenerative disease clinically called as a movement disorder. The PD is characterized by selective degeneration of dopaminergic neurons in the substantia nigra which is part of the midbrain thereby depleting the dopamine levels in the striatum and leads to several motor symptoms. Most of the current pharmaco-therapeutic approaches available now...

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  • PROTECTIVE EFFECT OF HUMAN UMBILICAL CORD BLOOD CELL ON CARDIOMYOPATHY IN MALE WISTAR RATS
    Rupali A Patil*, Prashant V Vyavahare, Chaitali M Diwane    Download Full Text

    This study examined the cardioprotective activity of human umbilical cord blood cells (hUCBC) in doxorubicin (Dxr) induced cardiomyopathy in Wistar rats. Wistar rats treated with doxorubicin (50 mg/kg i.p.) revealed cardiac damage that was manifested by the elevation of serum marker enzymes such as lactate dehydrogenase (LDH), aspartate aminotransaminase (AST) and alanine aminotransaminase (ALT). ...

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  • ETORICOXIB AND ESMOLOL PREVENTS VASCULAR OXIDATIVE STRESS IN RATS TREATED WITH ATHEROGENIC DIET AND TRITON WR1339
    Yash Prashar*, Ritu, Naresh Singh Gill    Download Full Text

    Atherosclerosis is no longer a disease attributed mainly to the high lipid content of the body but has come to be regarded as a chronic inflammatory disease with an autoimmune component. Atherosclerotic plaques occur preferentially in coronary arteries, where shear stress is oscillatory. Triton WR1339 and atherogenic diet causes decrease in shear stress leading to increased free radical production...

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  • A SHORT COMPREHENSIVE AND IMPERATIVE NOTE ON REGENERATIVE PHARMACOLOGY
    Devansh Mehta*, Parkhi Rastogi, Mohd Shuaib, Mohd Ali    Download Full Text

    Pharmacology is the science of drugs, and study of mechanism of action of drugs and lead compounds on the targets or target proteins or receptor molecules. Since ages, pharmacology and pharmaco-therapeutics have emerged and have been contributing to the health sciences and medical industry through its innovation and rigorous hard work in order to find innovative cure and treatment protocols, for ...

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  • A REVIEW ON BIOCHEMICAL MARKERS IN ACUTE CORONARY SYNDROME
    Reshma Nehere, D D Bandawane*    Download Full Text

    Cardiac biomarkers play a crucial role in accurate diagnosis of myocardial necrosis and for assessing risk and directing appropriate therapy that improves clinical outcome. The use of biomarkers in basic and clinical research as well as in clinical practice has become so common. The earliest biomarkers such as alanine aminotransferase and lactate dehydrogenase have fallen out of use with the devel...

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  • HEPATOPROTECTIVE ACTIVITY OF IGNORED MONOCOT GRASS KYLLINGA TRICEPS ROTTB.
    Amit Upadhyay*, Suman Jain, Neetu Bhalla, Kanika Arora, Subodh Dubey    Download Full Text

    The aim of present study was evaluation of in-vivo hepatoprotective activity of monocot grass Kyllinga triceps rottb. In the present study hepatotoxicity was induced by using CCl4, silymarin was taken as standard drug. Ethanolic and petroleum ether extracts were prepared for study. It was observed that among all the extracts of kyllinga triceps rottb, the petroleum ether extract significantly decr...

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